Chloramine-T

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Names

[ CAS No. ]:
127-65-1

[ Name ]:
Chloramine-T

[Synonym ]:
Euclorina
Chloramine (T)
CHLORAMINE-T-TRIHYDRATE
clorosan
CHLORAMINE-T, TRIHYDRATE OR - 250 G
Tosylchloramide sodium
MI 9
N-Chloro-4-toluenesulfonamide,sodium salt
NF X
Kloramin (VAN)
Sodium chloro[(4-methylphenyl)sulfonyl]azanide
MFCD00000522
Halamid
MeC6H4SO3NNaCl
Chloramine-T
MIANINE
Aktiven
N-CHLORO-4-TOLUOLSULFONAMID SODIUM
GANSIL
sodium N-chloro-p-toluenesulfonamide
Sodium chloro(tosyl)amide
Benzenesulfonamide, N-chloro-4-methyl-, sodium salt (1:1)
Chlorazene
CHLORAMINE T TRIHYDRATE
Clorina
Chloramine T
BENZENESULFONAMIDE,N-CHLORO-4-METHYL-, SODIUM SALT (1:1)
aktivin
anexol
EINECS 204-854-7

Chemical & Physical Properties

[ Density]:
1.36g/cm3

[ Boiling Point ]:
314.3ºC at 760mmHg

[ Melting Point ]:
167-170 °C(lit.)

[ Molecular Formula ]:
C7H7ClNNaO2S

[ Molecular Weight ]:
227.644

[ Flash Point ]:
143.9ºC

[ Exact Mass ]:
226.978378

[ PSA ]:
42.52000

[ LogP ]:
3.29200

[ Stability ]:
Stable. Incompatible with strong oxidizing agents. May decompose violently if heated above 130 C. May decompose on exposure to air.

[ Water Solubility ]:
H2O: >100 mg/mL

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XT5616800
CHEMICAL NAME :
p-Toluenesulfonamide, N-chloro-, sodium salt
CAS REGISTRY NUMBER :
127-65-1
LAST UPDATED :
199710
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C7-H8-Cl-N-O2-S.Na
MOLECULAR WEIGHT :
228.66
WISWESSER LINE NOTATION :
GMSWR DI &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
25 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - chronic pulmonary edema Lungs, Thorax, or Respiration - cyanosis
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
900 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - excitement Behavioral - muscle weakness
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - respiratory depression

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
100 ppm/24H
REFERENCE :
ARMCAH Annual Review of Medicine. (Annual Reviews, Inc., POB 10139, Palo Alto, CA 94303) V.1- 1950- Volume(issue)/page/year: 21,409,1970 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83916 No. of Facilities: 93 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 378 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83916 No. of Facilities: 190 (estimated) No. of Industries: 7 No. of Occupations: 8 No. of Employees: 1829 (estimated) No. of Female Employees: 1284 (estimated)

Safety Information

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R22;R31;R34;R42

[ Safety Phrases ]:
S22-S26-S36/37/39-S45-S7-S1/2

[ RIDADR ]:
UN 3263 8/PG 3

[ WGK Germany ]:
2

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-Toluenesulfonamide
  • Peraktivin

DownStream

  • Hydroxypyruvic acid
  • N-[diethylamino(phenyl)-λ4-sulfanylidene]-4-methylbenzenesulfonamide
  • p-Toluenesulfonyl isocyanate
  • Peraktivin
  • 4-Toluenesulfonamide
  • Glyceric Acid
  • D-Erythronic acid potassium salt
  • D-ARABINONIC ACID

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • chloramine-T
  • Chloramine-t
  • chloramine-T
  • Chloramine-T hydrate
  • Chloramine-T trihydrate
  • chloramine T trihydrate
  • (R)-2-((tert-Butoxycarbonyl)amino)-3-(2,3,6-trifluorophenyl)propanoic acid
  • 2-Amino-1-(2-methylpyridin-3-yl)propan-1-one
  • N-(cis-4-((6-Chloro-2-(trifluoromethyl)quinolin-4-yl)amino)cyclohexyl)-1H-pyrrolo[2,3-b]pyridine-4-carboxamide
  • Methyl 5-chloro-6-fluoro-1-benzofuran-3-carboxylate
  • {1-[(4-bromo-1-methyl-1H-pyrazol-5-yl)methyl]azetidin-2-yl}methanamine
  • 4-Amino-4-(2,6-difluorophenyl)cyclohexan-1-ol
  • (2R)-2-Bromohexadecanoic-9,10-t2 acid
  • O-{[1-(thian-3-yl)cyclopropyl]methyl}hydroxylamine
  • 5-(Propan-2-yl)-2-(propane-2-sulfonyl)cyclohexane-1-carboxylic acid
  • 5-(azepan-2-yl)-1H-1,2,3-triazole-4-carboxylic acid
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