Angiotensin II Receptor Ligand

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Names

[ CAS No. ]:
127060-75-7

[ Name ]:
Angiotensin II Receptor Ligand

[Synonym ]:
L-Isoleucine, N-[N-(diaminomethylene)-N-[(phenylmethoxy)carbonyl]-L-ornithyl]-N-[N-(3-pyridinylcarbonyl)-L-tyrosyl]-L-lysyl-L-histidyl-L-prolyl-
MFCD00133611
N-{N-[(Benzyloxy)carbonyl]-N-(diaminomethylene)-L-ornithyl}-N-[N-(3-pyridinylcarbonyl)-L-tyrosyl]-L-lysyl-L-histidyl-L-prolyl-L-isoleucine
CGP-42112

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C52H69N13O11

[ Molecular Weight ]:
1052.185

[ Exact Mass ]:
1051.523926

[ PSA ]:
365.14000

[ LogP ]:
2.38

[ Index of Refraction ]:
1.659

[ Storage condition ]:
2-8℃

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

Articles

Altered efficacy of AT1R-targeted treatment after spontaneous cancer cell-AT1R upregulation.

BMC Cancer 11 , 274, (2011)

Targeting of the renin angiotensin system (RAS) reduces tumour growth in experimental models of cancer. We aimed to establish if combined targeting of the 'classical' and 'alternative' arms of the RAS...

Update on the angiotensin AT(2) receptor.

Curr. Hypertens. Rep. 15(1) , 25-30, (2013)

It is quite well established that activation of the AT(2) receptor (AT(2)R) provides a counter-regulatory role to AT(1)R overactivity, particularly during pathological conditions. Indeed, a potential ...

Angiotensin III modulates the nociceptive control mediated by the periaqueductal gray matter

Neuroscience 164(3) , 1263-73, (2009)

Endogenous angiotensin (Ang) II and/or an Ang II-derived peptide, acting on Ang type 1 (AT1) and Ang type 2 (AT2) receptors, can carry out part of the nociceptive control modulated by periaqueductal g...


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Related Compounds

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