Angiotensin II Receptor Ligand
Suppliers
Names
[ CAS No. ]:
127060-75-7
[ Name ]:
Angiotensin II Receptor Ligand
[Synonym ]:
L-Isoleucine, N-[N-(diaminomethylene)-N-[(phenylmethoxy)carbonyl]-L-ornithyl]-N-[N-(3-pyridinylcarbonyl)-L-tyrosyl]-L-lysyl-L-histidyl-L-prolyl-
MFCD00133611
N-{N-[(Benzyloxy)carbonyl]-N-(diaminomethylene)-L-ornithyl}-N-[N-(3-pyridinylcarbonyl)-L-tyrosyl]-L-lysyl-L-histidyl-L-prolyl-L-isoleucine
CGP-42112
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Molecular Formula ]:
C52H69N13O11
[ Molecular Weight ]:
1052.185
[ Exact Mass ]:
1051.523926
[ PSA ]:
365.14000
[ LogP ]:
2.38
[ Index of Refraction ]:
1.659
[ Storage condition ]:
2-8℃
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
Articles
BMC Cancer 11 , 274, (2011)
Targeting of the renin angiotensin system (RAS) reduces tumour growth in experimental models of cancer. We aimed to establish if combined targeting of the 'classical' and 'alternative' arms of the RAS...
Curr. Hypertens. Rep. 15(1) , 25-30, (2013)
It is quite well established that activation of the AT(2) receptor (AT(2)R) provides a counter-regulatory role to AT(1)R overactivity, particularly during pathological conditions. Indeed, a potential ...
Neuroscience 164(3) , 1263-73, (2009)
Endogenous angiotensin (Ang) II and/or an Ang II-derived peptide, acting on Ang type 1 (AT1) and Ang type 2 (AT2) receptors, can carry out part of the nociceptive control modulated by periaqueductal g...