S(-)-5-FLUORO-8-HYDROXY-2-DIPROPYLAMINO-1,2,3,4-TETRAHYDRONAPHTHALENE HYDROCHLORIDE

Names

[ CAS No. ]:
127126-22-1

[ Name ]:
S(-)-5-FLUORO-8-HYDROXY-2-DIPROPYLAMINO-1,2,3,4-TETRAHYDRONAPHTHALENE HYDROCHLORIDE

[Synonym ]:
unii-1t7773jh5n

Chemical & Physical Properties

[ Boiling Point ]:
382ºC at 760 mmHg

[ Molecular Formula ]:
C₁₆H₂₅ClFNO

[ Molecular Weight ]:
301.82700

[ Flash Point ]:
184.8ºC

[ Exact Mass ]:
301.16100

[ PSA ]:
23.47000

[ LogP ]:
4.31260

[ Vapour Pressure ]:
2.22E-06mmHg at 25°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

In vivo intrinsic efficacy of the 5-HT1A receptor antagonists NAD-299, WAY-100,635 and (S)-(-)-UH-301 at rat brain monoamine receptors.

Eur. Neuropsychopharmacol. 9 , 15-19, (1999)

The receptor-mediated control of brain monoamine synthesis was used to examine the in vivo intrinsic efficacy of the 5-HT1A receptor antagonists NAD-299, S(-)-UH-301 and WAY-100,635. The rate of monoa...

Pharmacology of the novel 5-hydroxytryptamine1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: inhibition of (R)-8-hydroxy-2-(dipropylamino)tetralin-induced effects.

J. Pharmacol. Exp. Ther. 258 , 58, (1991)

The selective 5-hydroxytryptamine (5-HT1A) receptor agonist 8-hydroxy-2-(dipropylamino)tetralin (8-OH-DPAT) induces a large number of pharmacological effects. In the present study we demonstrate that ...

The 5-HT1A receptor selective ligands, (R)-8-OH-DPAT and (S)-UH-301, differentially affect the activity of midbrain dopamine neurons.

Naunyn Schmiedebergs Arch. Pharmacol. 347 , 353-362, (1993)

The effects of the selective 5-HT1A receptor agonist (R)-8-hydroxy-2(di-n-propylamino)tetralin [(R)-8-OH-DPAT] and the novel 5-HT1A antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)-tetralin [(S)-UH...