S(-)-5-FLUORO-8-HYDROXY-2-DIPROPYLAMINO-1,2,3,4-TETRAHYDRONAPHTHALENE HYDROCHLORIDE

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Names

[ CAS No. ]:
127126-22-1

[ Name ]:
S(-)-5-FLUORO-8-HYDROXY-2-DIPROPYLAMINO-1,2,3,4-TETRAHYDRONAPHTHALENE HYDROCHLORIDE

[Synonym ]:
unii-1t7773jh5n

Chemical & Physical Properties

[ Boiling Point ]:
382ºC at 760 mmHg

[ Molecular Formula ]:
C16H25ClFNO

[ Molecular Weight ]:
301.82700

[ Flash Point ]:
184.8ºC

[ Exact Mass ]:
301.16100

[ PSA ]:
23.47000

[ LogP ]:
4.31260

[ Vapour Pressure ]:
2.22E-06mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

In vivo intrinsic efficacy of the 5-HT1A receptor antagonists NAD-299, WAY-100,635 and (S)-(-)-UH-301 at rat brain monoamine receptors.

Eur. Neuropsychopharmacol. 9 , 15-19, (1999)

The receptor-mediated control of brain monoamine synthesis was used to examine the in vivo intrinsic efficacy of the 5-HT1A receptor antagonists NAD-299, S(-)-UH-301 and WAY-100,635. The rate of monoa...

Pharmacology of the novel 5-hydroxytryptamine1A receptor antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)tetralin: inhibition of (R)-8-hydroxy-2-(dipropylamino)tetralin-induced effects.

J. Pharmacol. Exp. Ther. 258 , 58, (1991)

The selective 5-hydroxytryptamine (5-HT1A) receptor agonist 8-hydroxy-2-(dipropylamino)tetralin (8-OH-DPAT) induces a large number of pharmacological effects. In the present study we demonstrate that ...

The 5-HT1A receptor selective ligands, (R)-8-OH-DPAT and (S)-UH-301, differentially affect the activity of midbrain dopamine neurons.

Naunyn Schmiedebergs Arch. Pharmacol. 347 , 353-362, (1993)

The effects of the selective 5-HT1A receptor agonist (R)-8-hydroxy-2(di-n-propylamino)tetralin [(R)-8-OH-DPAT] and the novel 5-HT1A antagonist (S)-5-fluoro-8-hydroxy-2-(dipropylamino)-tetralin [(S)-UH...


More Articles

Related Compounds

  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-methyl-1,2,3-thiadiazole-5-carboxylate
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-(difluoromethoxy)benzoate
  • Methyl 4-amino-6-chloropyridazine-3-carboxylate
  • (9H-fluoren-9-yl)methyl 2-(1-hydroxyethyl)azetidine-1-carboxylate
  • methyl 2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-(1-hydroxycyclohexyl)acetate
  • (9H-fluoren-9-yl)methyl N-(2-hydroxyethyl)-N-{[3-methyl-1-(propan-2-yl)-1H-pyrazol-4-yl]methyl}carbamate
  • (9H-fluoren-9-yl)methyl N-[2-hydroxy-4-(methylsulfanyl)butyl]carbamate
  • (9H-fluoren-9-yl)methyl 4-hydroxy-2,4-dimethylpiperidine-1-carboxylate
  • (9H-fluoren-9-yl)methyl N-(2-hydroxyethyl)-N-(3-methylpentan-2-yl)carbamate
  • (9H-fluoren-9-yl)methyl N-(1-hydroxy-3-methoxy-2-phenylpropan-2-yl)carbamate
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