PACAP-27 (human, mouse, ovine, porcine, rat) trifluoroacetate salt

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Names

[ Name ]:
PACAP-27 (human, mouse, ovine, porcine, rat) trifluoroacetate salt

[Synonym ]:
MFCD00167418
L-Leucinamide, L-histidyl-L-seryl-L-α-aspartylglycyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-α-aspartyl-L-seryl-L-tyrosyl-L-seryl-L-arginyl-L-tyrosyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl -L-alanyl-L-valyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alanyl-L-alanyl-L-valyl-
ADENYLATE CYCLASE ACTIVATING PEPTIDE-27
L-Histidyl-L-seryl-L-α-aspartylglycyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-α-aspartyl-L-seryl-L-tyrosyl-L-seryl-L-arginyl-L-tyrosyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-val yl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alanyl-L-alanyl-L-valyl-L-leucinamide
Talopram hydrochloride
PACAP (1-27), human, ovine, rat

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Molecular Formula ]:
C₁₄₂H₂₂₄N₄₀O₃₉S

[ Molecular Weight ]:
3147.608

[ Exact Mass ]:
3145.649414

[ PSA ]:
1340.85000

[ LogP ]:
-3.65

[ Appearance of Characters ]:
solid | white

[ Index of Refraction ]:
1.657

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

PACAP system evolution and its role in melanophore function in teleost fish skin.

Mol. Cell. Endocrinol. 411 , 130-45, (2015)

Pituitary adenylate cyclase-activating polypeptide (PACAP) administered to tilapia melanophores ex-vivo causes significant pigment aggregation and this is a newly identified function for this peptide ...

Pituitary adenylate cyclase activating polypeptide is an extraordinarily potent intra-pancreatic regulator of insulin secretion from islet beta-cells.

J. Biol. Chem. 269 , 1290-1293, (1994)

Insulin secretion from pancreatic islets is controlled by peptides as well as by nutrients. We report here a novel, extraordinarily potent peptidergic regulation of insulin secretion. A 27-residue for...

Pituitary adenylate cyclase-activating polypeptide increases [Ca2]i in rat gonadotrophs through an inositol trisphosphate-dependent mechanism.

J. Biol. Chem. 269 , 5680, (1994)

Pituitary adenylate cyclase-activating polypeptide (PACAP) increases cAMP production and stimulates hormone release from a variety of anterior pituitary cells. However, in anterior pituitary gonadotro...