CGP 39551

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Names

[ CAS No. ]:
127910-32-1

[ Name ]:
CGP 39551

[Synonym ]:
2-Amino-4-methyl-5-phosphono-3 pentenoic acid carboxyethyl ester

Chemical & Physical Properties

[ Density]:
1.312 g/cm3

[ Boiling Point ]:
434.1ºC at 760 mmHg

[ Melting Point ]:
236-239ºC

[ Molecular Formula ]:
C8H16NO5P

[ Molecular Weight ]:
237.19

[ Flash Point ]:
216.3ºC

[ Exact Mass ]:
237.07700

[ PSA ]:
119.66000

[ LogP ]:
0.70110

[ Vapour Pressure ]:
9.46E-09mmHg at 25°C

[ Index of Refraction ]:
1.512

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301

[ Precautionary Statements ]:
P301 + P310

[ RIDADR ]:
UN 2811 6.1 / PGIII

Precursor & DownStream

Precursor

  • CGP 37849
  • E-2-formylamino-4-methyl-5-dimethyl-phosphono-3-pentenoic acid ethyl ester
  • Bromo(trimethyl)silane
  • E-2-formylamino-4-methyl-5-diisopropylphosphono-3-pentenoic acid ethyl ester
  • E-2-formylamino-4-methyl-5-di(2-chloroethyl)phosphono-3-pentenoic acid ethyl ester

DownStream

  • CGP 37849

Articles

Competitive NMDA receptor antagonists and agonists: effects on spontaneous alternation in mice exposed to cerebral oligemia.

Pol. J. Pharmacol. 56(1) , 59-66, (2004)

The purpose of the present study was to investigate the effects of competitive NMDA receptor antagonists,D,L-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic acid (CGP 37849) and its ethyl ester (CGP 3955...

NMDA receptor antagonists acting at the glycineB site in rat models for antipsychotic-like activity.

J. Neural Transm. Gen. Sect. 106(11-12) , 1189-204, (1999)

Several partial agonist and full antagonists acting at the glycine site of the NMDA receptors were tested for potential antipsychotic-like properties in rats. As models, amphetamine- and phencyclidine...

Effects of competitive NMDA receptor antagonists on excitatory amino acid-evoked currents in mouse spinal cord neurones.

Fundam. Clin. Pharmacol. 13(1) , 67-74, (1999)

The effects of CGP 37849 [DL-(E)-2-amino-4-methyl-5-phosphono-3-pentenoate] and its ethylester CGP 39551 on whole-cell currents evoked by the endogenous excitatory amino acids, L-glutamate and L-aspar...


More Articles

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