cyclopenta-1,3-diene,cyclopentane,dichloroniobium

Names

[ CAS No. ]:
12793-14-5

[ Name ]:
cyclopenta-1,3-diene,cyclopentane,dichloroniobium

[Synonym ]:
MFCD00009949

Chemical & Physical Properties

[ Molecular Formula ]:
C10H10Cl2Nb

[ Molecular Weight ]:
293.99900

[ Exact Mass ]:
292.92200

[ LogP ]:
3.42200

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QU0400000
CHEMICAL NAME :
Niobium, dichlorobis(eta(sup 5)-2,4-cyclopentadien-1-yl)-
CAS REGISTRY NUMBER :
12793-14-5
LAST UPDATED :
198209
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C10-H10-Cl2-Nb
MOLECULAR WEIGHT :
294.01
WISWESSER LINE NOTATION :
G-NB-GR&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
35 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Skin and Appendages - hair Tumorigenic - active as anti-cancer agent
REFERENCE :
JINCAO Journal of Inorganic and Nuclear Chemistry. (Oxford, UK) V.1-43, 1955-81. Volume(issue)/page/year: 42,1789,1980

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
QU0400000

[ HS Code ]:
2903890090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,2-PHENYLENE PHOSPHOROCHLORIDITE
  • bis(cyclopentadienyl)niobium trihydride
  • DIETHYL CHLOROPHOSPHITE
  • (Cp)2Nb(η-1-(CH3)3CC5H4)Cl
  • (η2-disulfido)methyl-bis(η5-cyclopentadienyl)niobium

DownStream

Customs

[ HS Code ]: 2903890090

[ Summary ]:
2903890090. halogenated derivatives of cyclanic, cyclenic or cyclotherpenic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Articles

A (1)H NMR study of the interaction of antitumor metallocenes with glutathione.

J. Inorg. Biochem. 86(2-3) , 611-6, (2001)

The interaction of the antitumor active metallocene dihalides Cp(2)MCl(2) (M=Ti, Nb, Mo) and 1 equiv. of glutathione was studied by (1)H NMR spectroscopy at pD 2-7 in 4 mM NaCl solutions. No interacti...

Organometallic anticancer agents. 2. Aqueous chemistry and interaction of niobocene dichloride with nucleic acid constituents and amino acids.

J. Med. Chem. 39(25) , 5012-6, (1996)

The solution chemistry and interactions of niobocene dichloride, Cp2NbCl2, with nucleosides, nucleotides, and amino acids has been studied by 1H and 31P NMR spectroscopy. The 1H NMR spectrum of Cp2NbC...


More Articles

Related Compounds

  • cyclopenta-1,3-diene,cyclopentane,dibromozirconium
  • cyclopenta-1,3-diene,cyclopentane,sulfanide,sulfanylidenemolybdenum
  • cyclopenta-1,3-diene,cyclopentane,rhenium monohydride
  • cyclopenta-1,3-diene,cyclopentane,diiodozirconium
  • cyclopenta-1,3-diene,cyclopentane,diiodotitanium
  • cyclopenta-1,3-diene,cyclopentane,dibromotantalum
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