GDC-0032

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Names

[ CAS No. ]:
1282512-48-4

[ Name ]:
GDC-0032

[Synonym ]:
2-{4-[2-(1-Isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide
GDC-0032
RG7604
1H-Pyrazole-1-acetamide, 4-[5,6-dihydro-2-[3-methyl-1-(1-methylethyl)-1H-1,2,4-triazol-5-yl]imidazo[1,2-d][1,4]benzoxazepin-9-yl]-α,α-dimethyl-
S7103,GDC0032,RG7604
UNII-L08J2O299M
2-{3-[2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f ]imidazo[1,2-d][1,4]oxazepin-9-yl]-1H-pyrazol-1-yl}-2-methylpropanamide
2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanamide
2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanoic acid
Taselisib

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
783.3±70.0 °C at 760 mmHg

[ Molecular Formula ]:
C24H28N8O2

[ Molecular Weight ]:
460.531

[ Flash Point ]:
427.5±35.7 °C

[ Exact Mass ]:
460.233521

[ PSA ]:
119.66000

[ LogP ]:
0.69

[ Vapour Pressure ]:
0.0±2.7 mmHg at 25°C

[ Index of Refraction ]:
1.709

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanoic acid
  • IMidazo[1,2-d][1,4]benzoxazepine, 9-bromo-5,6-dihydro-2-[3-Methyl-1-(1-Methylethyl)-1H-1,2,4-triazol-5-yl]-
  • ethyl 2-(4-(2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)-1H-pyrazol-1-yl)-2-methylpropanoate
  • 4-Bromo-2-hydroxybenzaldehyde
  • 5-bromo-2-(1H-imidazol-2-yl)phenol
  • 9-bromo-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepine

DownStream

Related Compounds

  • GDC-0853
  • GDC-2394
  • GDC-0134
  • GDC-0068
  • L-Prolinamide, N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-N-(4-phenyl-1,2,3-thiadiazol-5-yl)-, monohydrochloride
  • GDC-0927 Racemate
  • 2'-(Trifluoromethyl)-6',7'-dihydro-5'H-spiro[cyclopropane-1,8'-[1,6]naphthyridin]-5'-one
  • 1-[2-Bromo-5-(trifluoromethyl)phenyl]cyclopropanecarboxaldehyde
  • 4,5-dimethyl-2-[(2S)-oxiran-2-yl]-1,3-oxazole
  • rel-(1R,2S)-6'-Bromo-2-fluoro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinolin]-1'-one
  • rel-(1R,2S)-2-Fluoro-6'-(trifluoromethyl)-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinolin]-1'-one
  • 1H,2H,3H,4H,8H,9H-furo[2,3-h]quinoline
  • Methyl 4-Bromo-2-(1-cyanocyclobutyl)benzoate
  • 6'-Bromo-2,2,5'-trifluoro-2',3'-dihydro-1'H-spiro[cyclopropane-1,4'-isoquinolin]-1'-one
  • Methyl 6-bromo-1-oxo-1,2,3,4-tetrahydroisoquinoline-4-carboxylate
  • 2-(6-bromo-1-oxo-spiro[3H-isoquinoline-4,1'-cyclopropane]-2-yl)-N-(1-methyl-2-oxo-pyrrolidin-3-yl)acetamide
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