Cinalukast
Suppliers
Names
[ CAS No. ]:
128312-51-6
[ Name ]:
Cinalukast
[Synonym ]:
Cinalukast
4-[3-[(E)-2-(4-cyclobutyl-1,3-thiazol-2-yl)ethenyl]anilino]-2,2-diethyl-4-oxobutanoic acid
Chemical & Physical Properties
[ Density]:
1.258g/cm3
[ Molecular Formula ]:
C23H28N2O3S
[ Molecular Weight ]:
412.54500
[ Exact Mass ]:
412.18200
[ PSA ]:
107.53000
[ LogP ]:
5.87360
[ Index of Refraction ]:
1.655
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Articles
J. Physiol. Pharmacol. 60(3) , 135-43, (2009)
Eryptosis, the suicidal death of erythrocytes, is characterized by cell shrinkage and cell membrane scrambling with phosphatidylserine exposure at the erythrocyte surface. Eryptosis is triggered by in...
J. Allergy Clin. Immunol. 99(2) , 210-5, (1997)
The degree and duration of protection against exercise-induced bronchoconstriction afforded by three doses of a specific leukotriene D4 receptor antagonist, cinalukast, were assessed after an initial ...
Biochem. Pharmacol. 44(7) , 1411-5, (1992)
We have identified and characterized two different subclasses of binding site for the novel peptido-leukotriene (LT) antagonist, [3H]ICI 198,615, in membranes from human lung parenchyma using a recept...