HIV Protease Substrate IV

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Names

[ CAS No. ]:
128340-47-6

[ Name ]:
HIV Protease Substrate IV

[Synonym ]:
HIV Substrate,KARVNleF(4-NO2)EANle-NH2

Chemical & Physical Properties

[ Molecular Formula ]:
C49H83N15O13

[ Molecular Weight ]:
1090.28000

[ Exact Mass ]:
1089.63000

[ PSA ]:
472.95000

[ LogP ]:
5.10380

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Characterization of the murine leukemia virus protease and its comparison with the human immunodeficiency virus type 1 protease.

J. Gen. Virol. 87(Pt 5) , 1321-30, (2006)

The protease (PR) of Murine leukemia virus (MLV) was expressed in Escherichia coli, purified to homogeneity and characterized by using various assay methods, including HPLC-based, photometric and fluo...

Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.

FEBS J. 272(20) , 5265-77, (2005)

HIV-1 protease (PR) and two drug-resistant variants--PR with the V82A mutation (PR(V82A)) and PR with the I84V mutation (PR(I84V))--were studied using reduced peptide analogs of five natural cleavage ...

Interactions of a novel inhibitor from an extremophilic Bacillus sp. with HIV-1 protease: implications for the mechanism of inactivation.

J. Biol. Chem. 276(4) , 2487-93, (2001)

The active site cleft of the HIV-1 protease (PR) is bound by two identical conformationally mobile loops known as flaps, which are important for substrate binding and catalysis. The present article re...


More Articles


Related Compounds

  • ANTHRANILYL-HIV PROTEASE SUBSTRATE IV
  • HIV Protease Substrate VI
  • HIV Protease Substrate VII
  • HIV Protease Substrate 1 TFA
  • HIV Protease Substrate III-B (Native Sequence)
  • hiv protease substrate iii
  • 4-(3,4-Dichlorophenyl)-4-(2,2,2-trifluoroacetamido)butanoic acid
  • 3-{[(Benzyloxy)carbonyl]({[4-(trifluoromethyl)phenyl]methyl})amino}propanoic acid
  • 2-(4-bromophenyl)-2-(2,2,2-trifluoro-N-methylacetamido)propanoic acid
  • benzyl N-(5-bromopyridin-2-yl)-N-[2-(pyridin-2-yl)ethyl]carbamate
  • benzyl N-[1-(4-bromo-3-methoxyphenyl)ethyl]carbamate
  • benzyl N-{1-[(4-bromo-1H-pyrazol-1-yl)methyl]-1-cyanoethyl}-N-methylcarbamate
  • benzyl N-(7-bromo-2-chloroquinazolin-4-yl)carbamate
  • benzyl N-cyclobutyl-N-(4-fluoro-2-iodophenyl)carbamate
  • tert-butyl N-(4-bromo-1-ethyl-1H-pyrazol-3-yl)carbamate
  • Benzyl 7-hydroxy-3-azabicyclo[3.3.1]nonane-3-carboxylate
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