HIV Protease Substrate IV

[ Molecular Formula ]:
C₄₉H₈₃N₁₅O₁₃

[ Molecular Weight ]:
1090.28000

[ Exact Mass ]:
1089.63000

[ PSA ]:
472.95000

[ LogP ]:
5.10380

Click to get detail MSDS

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Characterization of the murine leukemia virus protease and its comparison with the human immunodeficiency virus type 1 protease.

J. Gen. Virol. 87(Pt 5) , 1321-30, (2006)

The protease (PR) of Murine leukemia virus (MLV) was expressed in Escherichia coli, purified to homogeneity and characterized by using various assay methods, including HPLC-based, photometric and fluo...

Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 angstroms resolution crystal structures of HIV-1 protease mutants with substrate analogs.

FEBS J. 272(20) , 5265-77, (2005)

HIV-1 protease (PR) and two drug-resistant variants--PR with the V82A mutation (PR(V82A)) and PR with the I84V mutation (PR(I84V))--were studied using reduced peptide analogs of five natural cleavage ...

Interactions of a novel inhibitor from an extremophilic Bacillus sp. with HIV-1 protease: implications for the mechanism of inactivation.

J. Biol. Chem. 276(4) , 2487-93, (2001)

The active site cleft of the HIV-1 protease (PR) is bound by two identical conformationally mobile loops known as flaps, which are important for substrate binding and catalysis. The present article re...

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