N-[(2-chlorophenyl)methyl]-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide

Names

[ CAS No. ]:
128629-27-6

[ Name ]:
N-[(2-chlorophenyl)methyl]-4-hydroxy-2-oxo-1H-quinoline-3-carboxamide

Chemical & Physical Properties

[ Density]:
1.431g/cm3

[ Boiling Point ]:
549.3ºC at 760mmHg

[ Molecular Formula ]:
C17H13ClN2O3

[ Molecular Weight ]:
328.75000

[ Flash Point ]:
286ºC

[ Exact Mass ]:
328.06100

[ PSA ]:
85.94000

[ LogP ]:
3.80420

[ Vapour Pressure ]:
6.68E-13mmHg at 25°C

[ Index of Refraction ]:
1.666

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VB1171017
CHEMICAL NAME :
3-Quinolinecarboxamide, 1,2-dihydro-N-((2-chlorophenyl)methyl)-4-hydroxy-2-ox o-
CAS REGISTRY NUMBER :
128629-27-6
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C17-H13-Cl-N2-O3
MOLECULAR WEIGHT :
328.77

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 24(4),31,1990

Precursor & DownStream

Precursor

  • ethyl 2,4-dihydroxyquinoline-3-carboxylate
  • 2-Chlorobenzylamine

DownStream

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • (3R)-3-fluorobutyl 4-methylbenzene-1-sulfonate
  • tert-Butyl-DL-alanine
  • 1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-fluoro-3-[(prop-2-en-1-yl)sulfamoyl]benzoate