1,3-dimethyl-6-(2-methylphenyl)piperidine-3,4-diol

Names

[ CAS No. ]:
128887-73-0

[ Name ]:
1,3-dimethyl-6-(2-methylphenyl)piperidine-3,4-diol

Chemical & Physical Properties

[ Density]:
1.118g/cm3

[ Boiling Point ]:
376ºC at 760mmHg

[ Molecular Formula ]:
C₁₄H₂₁NO₂

[ Molecular Weight ]:
235.32200

[ Flash Point ]:
185ºC

[ Exact Mass ]:
235.15700

[ PSA ]:
43.70000

[ LogP ]:
1.42140

[ Vapour Pressure ]:
2.53E-06mmHg at 25°C

[ Index of Refraction ]:
1.563

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM7340090

CHEMICAL NAME :: 3,4-Piperidinediol, 1,3-dimethyl-6-(2-methylphenyl)-, (1-alpha,3-alpha,4-beta,6-beta)-

CAS REGISTRY NUMBER :: 128887-73-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H21-N-O2

MOLECULAR WEIGHT :: 235.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 228 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory stimulation Lungs, Thorax, or Respiration - other changes

REFERENCE :: KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 24(2),114,1990

Precursor & DownStream

Precursor

(2R,5R)-5-hydroxy-1,5-dimethyl-2-(o-tolyl)piperidin-4-one
(E)-1-(2-methyloxiran-2-yl)-3-(o-tolyl)prop-2-en-1-one

DownStream

Related Compounds

4-ethyl-1,3-dimethyl-6-(2-methylphenyl)piperidine-3,4-diol
(3S,4R,6S)-4-ethynyl-1,3-dimethyl-6-(2-methylphenyl)piperidine-3,4-diol
1,3-dimethyl-6-(2,4,5-trimethylphenyl)piperidine-3,4-diol
(3S,4R,6S)-1,3-dimethyl-6-(4-methylphenyl)piperidine-3,4-diol
(3S,4S,6S)-1,3-dimethyl-6-(4-methylphenyl)piperidine-3,4-diol,hydrochloride
(3S,4R,6S)-4-ethynyl-1,3-dimethyl-6-(4-methylphenyl)piperidine-3,4-diol