phenylbutazone sodium
Suppliers
Names
[ CAS No. ]:
129-18-0
[ Name ]:
phenylbutazone sodium
[Synonym ]:
PHENYLBUTAZONE SODIUM
3,5-dioxo-1,2-diphenyl-4-n-butylpyrazolidinsodium
4-BUTYL-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE SODIUM
Einecs 204-935-7
diphenyldioxobutylpyrazolidine-butazolidine-sodium
Phenylbutazone sodium salt
PHENYL BUTAZONE SODIUM SALT
sodiumphenylbutazone
MFCD01749404
Sodium 4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-ide
UNII:189M850I32
butazolidinesodium
Chemical & Physical Properties
[ Density]:
1.063 g/mL at 25 °C(lit.)
[ Boiling Point ]:
113 °C27 mm Hg(lit.)
[ Molecular Formula ]:
C19H19N2NaO2
[ Molecular Weight ]:
330.356
[ Flash Point ]:
95 °C
[ Exact Mass ]:
330.134430
[ PSA ]:
49.99000
[ LogP ]:
4.11460
[ Index of Refraction ]:
n20/D 1.516(lit.)
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ8300000
- CHEMICAL NAME :
- 3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-, monosodium salt
- CAS REGISTRY NUMBER :
- 129-18-0
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C19-H20-N2-O2.Na
- MOLECULAR WEIGHT :
- 331.40
- WISWESSER LINE NOTATION :
- T5VNNV EHJ BR& CR& E4 &-NA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 16 mg/kg/D
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Blood - agranulocytosis Skin and Appendages - dermatitis, other (after systemic exposure)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 855 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 310 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 113 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 476 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 169 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 257 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 94 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 146 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Human Lymphocyte
- DOSE/DURATION :
- 2160 umol/L
- REFERENCE :
- HUMAA7 Humangenetik. (Heidelberg, Fed. Rep. Ger.) V.1-30, 1964-75. For publisher information, see HUGEDQ. Volume(issue)/page/year: 12,330,1971
Safety Information
[ Hazard Codes ]:
C
[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .
[ Safety Phrases ]:
S26-S36
[ HS Code ]:
2934100090
Customs
[ HS Code ]: 2934100090
[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%