GR 82334

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Names

[ CAS No. ]:
129623-01-4

[ Name ]:
GR 82334

Chemical & Physical Properties

[ Molecular Formula ]:
C69H91N15O16

[ Molecular Weight ]:
1386.55000

[ Exact Mass ]:
1385.68000

[ PSA ]:
479.25000

[ LogP ]:
3.53680

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Effect of tachykinins on ascending and descending reflex pathway in rat small intestine.

Acta Pharmacol. Sin. 23(4) , 289-95, (2002)

To examine the effect of tachykinins on the ascending reflex pathway in rat small intestine, we used different selective neurokinin (NK) receptor antagonists (RA): a) NK1-RA: GR-82334 and CP-96.345, b...

Substance P modulates localized calcium transients and membrane current responses in murine colonic myocytes.

Br. J. Pharmacol. 138(7) , 1233-43, (2003)

1. Neurokinins contribute to the neural regulation of gastrointestinal (GI) smooth muscles. We studied responses of murine colonic smooth muscle cells to substance P (SP) and NK(1) and NK(2) agonists ...

Characterization of receptors for two Xenopus gastrointestinal tachykinin peptides in their species of origin.

Naunyn Schmiedebergs Arch. Pharmacol. 370(1) , 35-45, (2004)

Two tachykinin peptides, bufokinin and Xenopus neurokinin A (X-NKA) were recently isolated from Xenopus laevis. In this study we investigated the tachykinin receptors in the Xenopus gastrointestinal t...


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Related Compounds

  • GR 144053 trihydrochloride
  • GR 46611
  • GR 89696 free base
  • GR 94800 TFA
  • GR 203040
  • GR 159897
  • 2-azido-N-(3,4-dimethylphenyl)acetamide
  • 2-(1-(3,5-dimethoxybenzyl)-1H-indol-3-yl)-N-(thiazol-2-yl)acetamide
  • 2-(1-(3,5-dimethoxybenzyl)-1H-indol-3-yl)-N-methylacetamide
  • N-(cyclopropylmethyl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridin-5-amine
  • 4',3,5-Trifluorobiphenyl-4-carboxylic acid
  • 1-(2-(1-(3,5-dimethoxybenzyl)-1H-indol-3-yl)acetyl)piperidine-4-carboxamide
  • 4-(2-(1-(3,5-dimethoxybenzyl)-1H-indol-3-yl)acetamido)benzamide
  • 6-chloro-N-(2-(thiophen-2-yl)ethyl)pyridazin-3-amine
  • S-4-Hydroxyalprazolam
  • 3,5-Difluoro-4-(2-fluorophenyl)pyridine