GR 82334

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Names

[ CAS No. ]:
129623-01-4

[ Name ]:
GR 82334

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₉H₉₁N₁₅O₁₆

[ Molecular Weight ]:
1386.55000

[ Exact Mass ]:
1385.68000

[ PSA ]:
479.25000

[ LogP ]:
3.53680

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Effect of tachykinins on ascending and descending reflex pathway in rat small intestine.

Acta Pharmacol. Sin. 23(4) , 289-95, (2002)

To examine the effect of tachykinins on the ascending reflex pathway in rat small intestine, we used different selective neurokinin (NK) receptor antagonists (RA): a) NK1-RA: GR-82334 and CP-96.345, b...

Substance P modulates localized calcium transients and membrane current responses in murine colonic myocytes.

Br. J. Pharmacol. 138(7) , 1233-43, (2003)

1. Neurokinins contribute to the neural regulation of gastrointestinal (GI) smooth muscles. We studied responses of murine colonic smooth muscle cells to substance P (SP) and NK(1) and NK(2) agonists ...

Characterization of receptors for two Xenopus gastrointestinal tachykinin peptides in their species of origin.

Naunyn Schmiedebergs Arch. Pharmacol. 370(1) , 35-45, (2004)

Two tachykinin peptides, bufokinin and Xenopus neurokinin A (X-NKA) were recently isolated from Xenopus laevis. In this study we investigated the tachykinin receptors in the Xenopus gastrointestinal t...

GR 144053 trihydrochloride
GR 46611
GR 89696 free base
GR 94800 TFA
GR 203040
GR 159897
N-[(3,5-dimethylisoxazol-4-yl)methyl]-1-(2-fluorophenyl)-5-pyridin-2-yl-1H-1,2,3-triazole-4-carboxamide
2-Acetamido-N-{1-[6-(3-fluorophenyl)pyridazin-3-YL]piperidin-4-YL}acetamide
N-{1-[6-(3-fluorophenyl)pyridazin-3-yl]piperidin-4-yl}isonicotinamide
N-{1-[6-(3-fluorophenyl)pyridazin-3-yl]piperidin-4-yl}-3-methylthiophene-2-carboxamide
N-(1-(6-(3-fluorophenyl)pyridazin-3-yl)piperidin-4-yl)thiophene-3-carboxamide
3-[3-(4-chlorophenoxy)propyl]-1H-indole-2-carboxylic acid
2-((2-oxo-3-(pyrrolidin-1-ylsulfonyl)pyridin-1(2H)-yl)methyl)-4H-pyrido[1,2-a]pyrimidin-4-one
1-((5-methyl-2-phenyloxazol-4-yl)methyl)-3-(pyrrolidin-1-ylsulfonyl)pyridin-2(1H)-one
3-(Pyrrolidine-1-sulfonyl)-1-{[2-(trifluoromethoxy)phenyl]methyl}-1,2-dihydropyridin-2-one
1-(2-(2-chlorophenyl)-2-oxoethyl)-3-(pyrrolidin-1-ylsulfonyl)pyridin-2(1H)-one

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