GR 82334
Suppliers
Names
[ CAS No. ]:
129623-01-4
[ Name ]:
GR 82334
Chemical & Physical Properties
[ Molecular Formula ]:
C69H91N15O16
[ Molecular Weight ]:
1386.55000
[ Exact Mass ]:
1385.68000
[ PSA ]:
479.25000
[ LogP ]:
3.53680
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
Articles
Acta Pharmacol. Sin. 23(4) , 289-95, (2002)
To examine the effect of tachykinins on the ascending reflex pathway in rat small intestine, we used different selective neurokinin (NK) receptor antagonists (RA): a) NK1-RA: GR-82334 and CP-96.345, b...
Br. J. Pharmacol. 138(7) , 1233-43, (2003)
1. Neurokinins contribute to the neural regulation of gastrointestinal (GI) smooth muscles. We studied responses of murine colonic smooth muscle cells to substance P (SP) and NK(1) and NK(2) agonists ...
Naunyn Schmiedebergs Arch. Pharmacol. 370(1) , 35-45, (2004)
Two tachykinin peptides, bufokinin and Xenopus neurokinin A (X-NKA) were recently isolated from Xenopus laevis. In this study we investigated the tachykinin receptors in the Xenopus gastrointestinal t...