Y-27632 2HCl

Suppliers

Names

[ Name ]:
Y-27632 2HCl

[Synonym ]:
trans-4-[(1R)-1-Aminoethyl]-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride
(R)-(+)-trans-4-(1-Aminoethyl)-N-(4-Pyridyl)cyclohexanecarboxamide dihydrochloride
Y-27632 (hydrochloride)
Y-27632 dihydrochloride
Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl-, trans-, hydrochloride (1:2)
trans-4-[(1R)-1-Aminoethyl]-N-(4-pyridinyl)cyclohexanecarboxamide dihydrochloride
Y-27632 2HCL
(+)-trans-N-(4-Pyridyl)-4-[(R)-1-aminoethyl]cyclohexanecarboxamide dihydrochloride
trans-4-[(R)-1-Aminoethyl]-N-(4-pyridyl)cyclohexanecarboxamide dihydrochloride
Y27632 2HCl
Y-27632 (dihydrochloride)

Chemical & Physical Properties

[ Melting Point ]:
258℃

[ Molecular Formula ]:
C₁₄H₂₃Cl₂N₃O

[ Molecular Weight ]:
320.258

[ Exact Mass ]:
319.121826

[ PSA ]:
68.01000

[ LogP ]:
4.55100

[ Appearance of Characters ]:
white to beige

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: soluble14mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332

[ Precautionary Statements ]:
P261-P280-P301 + P312 + P330

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21/22

[ Safety Phrases ]:
36

[ RIDADR ]:
NONH for all modes of transport

Articles

Actin-mediated gene expression depends on RhoA and Rac1 signaling in proximal tubular epithelial cells.

PLoS ONE 10(3) , e0121589, (2015)

Morphological alterations of cells can lead to modulation of gene expression. An essential link is the MKL1-dependent activation of serum response factor (SRF), which translates changes in the ratio o...

Rho-kinase signaling controls nucleocytoplasmic shuttling of class IIa histone deacetylase (HDAC7) and transcriptional activation of orphan nuclear receptor NR4A1.

Biochem. Biophys. Res. Commun. 459(2) , 179-83, (2015)

Rho-kinase (ROCK) has been well documented to play a key role in RhoA-induced actin remodeling. ROCK activation results in myosin light chain (MLC) phosphorylation either by direct action on MLC kinas...

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration.

Nature 494 , 247-50, (2013)

The Wnt target gene Lgr5 (leucine-rich-repeat-containing G-protein-coupled receptor 5) marks actively dividing stem cells in Wnt-driven, self-renewing tissues such as small intestine and colon, stomac...

Y-27632
N-Boc-Y-27632
Cyclohexanecarboxamide, 4-[(1R)-1-aminoethyl]-N-4-pyridinyl- (9CI)
Y-29794 OXALATE
Y-39983 HCl
Y-320
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
5-Cyclopropyl-2-(trifluoromethoxy)pyridine
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
Ethyl 2-(4,5-dibromo-2H-1,2,3-triazol-2-yl)-5-fluoro-3-pyridinecarboxylate
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
(S)-6-Fluoro-7-(trifluoromethyl)chroman-4-amine
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde