DIMETHYLANILINE
Suppliers
Names
[ CAS No. ]:
1300-73-8
[ Name ]:
DIMETHYLANILINE
[Synonym ]:
Xylidines,Mixed
EINECS 215-091-4
DMAmixture
XYLIDINES
Dimethylaniline
xylidinen
MFCD00167021
xilidine
aminoxylene
XYLIDINE
Chemical & Physical Properties
[ Density]:
0,98 g/cm3
[ Boiling Point ]:
221.9ºC at 760mmHg
[ Molecular Formula ]:
C48H66N6
[ Molecular Weight ]:
727.07800
[ Flash Point ]:
97°C
[ Exact Mass ]:
726.53500
[ PSA ]:
156.12000
[ LogP ]:
14.80080
[ Vapour Pressure ]:
0.154mmHg at 25°C
[ Index of Refraction ]:
1.559
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ZE8575000
- CHEMICAL NAME :
- Xylidine
- CAS REGISTRY NUMBER :
- 1300-73-8
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 37
- MOLECULAR FORMULA :
- C8-H11-N
- MOLECULAR WEIGHT :
- 121.20
- WISWESSER LINE NOTATION :
- ZR X1 X1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 610 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,1,1949
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(10),5,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1670 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(10),5,1976
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - cat
- DOSE/DURATION :
- 120 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,1,1949
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 600 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 34ZIAG "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969 Volume(issue)/page/year: -,637,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 20(10),5,1976
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 240 mg/kg
- REFERENCE :
- JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 31,1,1949 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 2.5 mg/m3 (0.5 ppm) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 5 ppm (25 mg/m3) (skin) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,282,1971 OSHA PEL (Gen Indu):8H TWA 5 ppm (25 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 5 ppm (25 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 5 ppm (25 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 5 ppm (25 mg/m3) (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 5 ppm (25 mg/m3);Skin JAN 1993 OEL-AUSTRALIA:TWA 2 ppm (10 mg/m3);Skin JAN 1993 OEL-BELGIUM:TWA 2 ppm (9.9 mg/m3);Skin JAN 1993 OEL-DENMARK:TWA 2 ppm (10 mg/m3);Skin JAN 1993 OEL-FINLAND:TWA 5 ppm (25 mg/m3);STEL 10 ppm (50 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 2 ppm (10 mg/m3);Skin JAN 1993 OEL-GERMANY:TWA 5 ppm (25 mg/m3);Skin JAN 1993 OEL-HUNGARY:TWA 5 mg/m3;STEL 20 mg/m3;Skin JAN 1993 OEL-THE NETHERLANDS:TWA 2 ppm (10 mg/m3);Skin JAN 1993 OEL-THE PHILIPPINES:TWA 100 ppm (435 mg/m3);Skin JAN 1993 OEL-RUSSIA:STEL 3 mg/m3;Skin JAN 1993 OEL-SWITZERLAND:TWA 2 ppm (10 mg/m3);Skin JAN 1993 OEL-TURKEY:TWA 5 ppm (25 mg/m3);Skin JAN 1993 OEL-UNITED KINGDOM:TWA 2 ppm (10 mg/m3);STEL 10 ppm;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO XYLIDINE-air:10H TWA 2 ppm (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 76910 No. of Facilities: 110 (estimated) No. of Industries: 5 No. of Occupations: 7 No. of Employees: 1754 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 76910 No. of Facilities: 432 (estimated) No. of Industries: 8 No. of Occupations: 11 No. of Employees: 2319 (estimated) No. of Female Employees: 316 (estimated)
Safety Information
[ Risk Phrases ]:
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed . R33:Danger of cumulative effects. R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
[ Safety Phrases ]:
S28-S36/37-S45
[ RIDADR ]:
1711
[ RTECS ]:
ZE8575000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2921492000
Customs
[ HS Code ]: 2921492000
[ Summary ]:
2921492000 n,n-dimethylaniline。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:6.5%。General tariff:20.0%