3-Chloropropyl isocyanate

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Names

[ CAS No. ]:
13010-19-0

[ Name ]:
3-Chloropropyl isocyanate

[Synonym ]:
Propane, 1-chloro-3-isocyanato-
1-Chloro-3-isocyanatopropane
3-Chloropropyl isocyanate
MFCD00010384

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
156.0±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C4H6ClNO

[ Molecular Weight ]:
119.549

[ Flash Point ]:
58.7±11.8 °C

[ Exact Mass ]:
119.013794

[ PSA ]:
29.43000

[ LogP ]:
1.82

[ Vapour Pressure ]:
3.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.460

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S23-S26-S27-S28-S36/37/39-S36/37

[ RIDADR ]:
UN 2206 6.1/PG 3

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
6.1

[ HS Code ]:
2929109000

Synthetic Route

Precursor & DownStream

Precursor

  • 4-Chlorobutyryl chloride
  • Carbamic acid,(3-chloropropyl)-, ethyl ester (6CI,9CI)
  • phosgene
  • 1-Chloronaphthalene
  • 3-Methoxypropylamine
  • Toluene

DownStream

  • Urea,N,N'-bis(3-chloropropyl)-
  • (2-cyanophenyl) N-(3-chloropropyl)carbamate
  • 1-[3-(2-oxo-1,3-diazinan-1-yl)phenyl]-1,3-diazinan-2-one

Customs

[ HS Code ]: 2929109000

[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Proline-linked nitrosoureas as prolidase-convertible prodrugs in human breast cancer cells.

Pharmacol. Rep. 60(2) , 171-82, (2008)

A number of novel proline-linked nitrosoureas (1-4) were synthesized and examined for cytotoxicity and influence on DNA and collagen biosynthesis in MDA-MB-231 and MCF-7 human breast cancer cells. Eva...

Imidazo [1', 2': 3, 4] pyrimido [6, 1-a] isoquinoline and Pyrimido [1', 2': 3, 4] pyrimido [6, 1-a] isoquinoline Ring Systems by Tandem Cyclization. Fülöp F, et al.

Synthesis 1995(07) , 863-67, (1995)

One-pot Syntheses of Fused Quinazolines by Reaction of N-(2-Cyanophenyl) chloromethanimidoyl Chloride. I. A New Synthesis of 1, 3-Oxazolo-and 1, 3-Oxazino [2, 3-b] quinazolines. Divišová H, et al.

Molecules 5(10) , 1166-74, (2000)


More Articles


Related Compounds

  • 3-chloropropyl-2-furfurylsulfide
  • (3-chloropropyl)pentamethyldisiloxane
  • (3-chloropropyl)-ethoxy-dichlorosilane
  • 3-chloropropyl 3,4,5-trimethoxybenzoate
  • 3-chloropropyl(triethyl)silane
  • (3-chloropropyl)cyclohexane
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-{1-[6-(Pyrrolidin-1-yl)pyridin-3-yl]cyclopropyl}cyclopropan-1-amine
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4-[3-cyclopropyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanamido]-2-hydroxybutanoic acid
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine