H-D-Phe-Ome HCl

Suppliers

Names

[ Name ]:
H-D-Phe-Ome HCl

[Synonym ]:
Methyl D-phenylalaninate hydrochloride (1:1)
MFCD00066112
H-D-Phe-OMe·HCl
L-Phenylalanine, methyl ester, hydrochloride (1:1)
D-Phenylalanine Methyl Ester Hydrochloride
EINECS 219-934-7
D-Phenylalanine, methyl ester, hydrochloride (1:1)
Methyl L-phenylalaninate hydrochloride (1:1)
methyl (2R)-2-amino-3-phenylpropanoate,hydrochloride
L-Phenylalanine methyl ester hydrochloride
H-D-Phe-OMe.HCl
H-D-Phe-Ome HCl

Chemical & Physical Properties

[ Density]:
1.1g/cm3

[ Boiling Point ]:
264.2ºC at 760 mmHg

[ Melting Point ]:
159-163 °C(lit.)

[ Molecular Formula ]:
C₁₀H₁₄ClNO₂

[ Molecular Weight ]:
215.677

[ Flash Point ]:
126ºC

[ Exact Mass ]:
215.071304

[ PSA ]:
52.32000

[ LogP ]:
2.23170

[ Vapour Pressure ]:
0.00986mmHg at 25°C

[ Index of Refraction ]:
-37.0 ° (C=2, EtOH)

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2923900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

D-phenylalanine
Methanol
2,2-Dimethoxypropane
Boc-D-Phe-OH
dl-phenylalanine methyl ester hydrochloride
methyl (2R)-3-phenyl-2-(phenylmethoxycarbonylamino)propanoate
Benzyl bromide
N-Benzyloxy-D-phenylalanin-methylester
methyl 2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoate

DownStream

METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
D-phenylalaninol
Cyclo(Ala-Phe)
Cyclo(Phe-Val)
D-phenylalanine
(2R)-3-PHENY-1,2-PROPANEDIAMINE
tert-Butyl-[(2R)-1-oxo-3-phenylpropan-2-yl]carbamat
D-Phenylalaninamide hydrochloride
Nateglinide
(2s,3r)-3-amino-2-hydroxy-4-phenylbutyric acid hydrochloride

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

N-methyl phenylalanine-rich peptides as highly versatile blood-brain barrier shuttles.

J. Med. Chem. 53 , 2354-63, (2010)

Here we studied the capacity of N-MePhe-(N-MePhe)(3)-CONH(2), Cha-(N-MePhe)(3)-CONH(2), and 2Nal-(N-MePhe)(3)-CONH(2) to carry various drugs (cargos) in in vitro blood-brain barrier (BBB) models in or...

Spectrum of toxicities of amino acid methyl esters for myeloid cells is determined by distinct metabolic pathways.

Blood 79(4) , 964-71, (1992)

L-leucine methyl ester (Leu-OMe), Leu-Leu-OMe, Phe-OMe, and Glu-(OMe)2 are toxic to mononuclear phagocytes (M phi) and neutrophils. In the present studies, the mechanism of this toxicity was examined....

Enzyme activity evaluation of organic solvent-treated phenylalanine ammonia lyase.

Biotechnol. Prog. 27(6) , 1554-60, (2011)

The direct one-step synthesis of L-phenylalanine methyl ester in an organic-aqueous biphasic system using phenylalanine ammonia lyase (E.C.4.3.1.5, PAL) containing Rhodotorula glutinis yeast whole cel...

H-M-FLUORO-D-PHE-OME HCL
4-Chloro-D-Phe-OMe·HCl
4-Nitro-D-phenylalanine methyl ester monohydrochloride
H-D-Phe-Obut HCl
h-d-chg-ome hcl
H-D-Phe(4-Cl)-OH.HCl
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Benzenemethanamine, |A-cyclopropyl-4-methyl-3-(trifluoromethyl)-
tert-Butyl 3-(4-methoxy-4-oxobutyl)azetidine-1-carboxylate
5-chloro-N'-hydroxy-3-methylpyridine-2-carboximidamide
2-{[4-Chloro-3-(trifluoromethyl)phenyl]azamethylene}-5-[(4-fluorophenyl)methyl ene]-1,3-thiazolidin-4-one
2-(3-Methylfuran-2-yl)piperidine
5-Chloro-1-[2-(difluoromethoxy)ethyl]pyrazol-4-amine
2-(3-Aminobutyl)benzene-1,4-diol
4-(4-Bromophenyl)-2,6-dinaphthalen-1-ylpyrimidine

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