Exendin-3 trifluoroacetate salt

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Names

[ CAS No. ]:
130357-25-4

[ Name ]:
Exendin-3 trifluoroacetate salt

[Synonym ]:
MFCD00240170

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈₄H₂₈₂N₅₀O₆₁S

[ Molecular Weight ]:
4202.57

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas.

J. Biol. Chem. 267 , 7402, (1992)

The recent identification in Heloderma horridum venom of exendin-3, a new member of the glucagon superfamily that acts as a pancreatic secretagogue, prompted a search for a similar peptide in Heloderm...

Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line.

J. Clin. Invest. 101 , 1334-1341, (1998)

To examine the influence of the putative satiety factor (GLP-1) on the hypothalamo-pituitary-gonadal axis, we used GT1-7 cells as a model of neuronal luteinizing hormone- releasing hormone (LHRH) rele...

Glucagon receptor knockout mice display increased insulin sensitivity and impaired beta-cell function.

Diabetes 55(12) , 3463-9, (2006)

In previous studies, glucagon receptor knockout mice (Gcgr(-/-)) display reduced blood glucose and increased glucose tolerance, with hyperglucagonemia and increased levels of glucagon-like peptide (GL...

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