Batimastat

Suppliers

Names

[ Name ]:
Batimastat

[Synonym ]:
(2R,3S)-N-Hydroxy-2-isobutyl-N-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-3-[(2-thienylsulfanyl)methyl]succinamide
(2R,3S)-N-hydroxy-N-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-2-(2-methylpropyl)-3-[(thiophen-2-ylsulfanyl)methyl]butanediamide
(2S,3R)-5-Methyl-3-(((aS)-a-(methylcarbamoyl)phenethyl)carbamoyl)-2-((2-thienylthio)methyl)hexanohydroxamic Acid
(2R,3S)-N-Hydroxy-2-isobutyl-N-[(2S)-1-(methylamino)-1-oxo-3-phenyl-2-propanyl]-3-[(2-thienylsulfanyl)methyl]succinamide
BB-94
Butanediamide, N-hydroxy-N-[(1S)-2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]-, (2R,3S)-
Batimastat (BB-94)
[2R-[1(S*),2R*,3S*]]-N4-Hydroxy-N1-[2-(methylamino)-2-oxo-1-(phenylmethyl)ethyl]-2-(2-methylpropyl)-3-[(2-thienylthio)methyl]butane Diamide
1rm8
Batimastat

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Melting Point ]:
236-238°

[ Molecular Formula ]:
C₂₃H₃₁N₃O₄S₂

[ Molecular Weight ]:
477.640

[ Exact Mass ]:
477.175598

[ PSA ]:
161.07000

[ LogP ]:
3.53

[ Appearance of Characters ]:
white to tan

[ Index of Refraction ]:
1.605

[ Storage condition ]:
Store at -20°C

[ Water Solubility ]:
DMSO: ≥15mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
29349990

Articles

The sorting protein PACS-2 promotes ErbB signalling by regulating recycling of the metalloproteinase ADAM17.

Nat. Commun. 6 , 7518, (2015)

The metalloproteinase ADAM17 activates ErbB signalling by releasing ligands from the cell surface, a key step underlying epithelial development, growth and tumour progression. However, mechanisms acut...

Inside-out Regulation of Ectodomain Cleavage of Cluster-of-Differentiation-44 (CD44) and of Neuregulin-1 Requires Substrate Dimerization.

J. Biol. Chem. 290 , 17041-54, (2015)

Ectodomain shedding of transmembrane precursor proteins generates numerous life-essential molecules, such as epidermal growth factor receptor ligands. This cleavage not only releases the regulatory gr...

Prevention of abdominal aortic aneurysm progression by targeted inhibition of matrix metalloproteinase activity with batimastat-loaded nanoparticles.

Circ. Res. 117 , e80-9, (2015)

Matrix metalloproteinases (MMPs)-mediated extracellular matrix destruction is the major cause of development and progression of abdominal aortic aneurysms. Systemic treatments of MMP inhibitors have s...

Batimastat sodium salt
2-(2-Bromobenzo[d]oxazol-4-yl)acetonitrile
8-Bromo-1-(difluoromethoxy)isoquinoline
2-(2-Amino-4-(chloromethyl)-5-(difluoromethyl)pyridin-3-yl)acetonitrile
1-Methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid
5-(Difluoromethyl)-3-methoxy-4-nitropyridin-2-amine
6-Amino-5-(difluoromethyl)pyridin-2-ol
2-Bromo-4-(difluoromethyl)-5-iodo-3-nitropyridine
2-(2-Bromo-6-(bromomethyl)-4-(difluoromethyl)pyridin-3-yl)acetic acid
2-Bromo-4-(difluoromethyl)-5-methoxynicotinonitrile
6-Ethoxy-2-methylquinazolin-4-amine

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