A-68930 hydrochloride

Suppliers

Names

[ CAS No. ]:
130465-39-3

[ Name ]:
A-68930 hydrochloride

[Synonym ]:
cis-1-(Aminomethyl)-3-phenylisochroman-5,6-diol hydrochloride
(1R,3S)-1-(aminomethyl)-3-phenyl-3,4-dihydro-1H-isochromene-5,6-diol,hydrochloride

Chemical & Physical Properties

[ Melting Point ]:
250ºC

[ Molecular Formula ]:
C16H18ClNO3

[ Molecular Weight ]:
307.77200

[ Exact Mass ]:
307.09800

[ PSA ]:
75.71000

[ LogP ]:
3.91390

[ Storage condition ]:
-20°C

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2932999099

Synthetic Route

Precursor & DownStream

Precursor

  • Styrene oxide
  • 2-[2',3'-(cyclohexylidenedioxy)phenyl]-1-phenylethanone
  • 1-phenyl-2-(spiro[benzo[d][1,3]dioxole-2,1'-cyclohexan]-4-yl)ethanol
  • spiro[1,3-benzodioxole-2,1'-cyclohexane]
  • ((6R,8S)-8-phenyl-8,9-dihydro-6H-spiro[[1,3]dioxolo[4,5-f]isochromene-2,1'-cyclohexan]-6-yl)methanamine
  • (1S)-2-[2',3'-(cyclohexylidenedioxy)phenyl]-1-phenylethanol
  • (6R,8S)-6-(bromomethyl)-8-phenyl-8,9-dihydro-6H-spiro[[1,3]dioxolo[4,5-f]isochromene-2,1'-cyclohexane]

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

A-68930, a novel, potent dopamine D1 receptor agonist: a microstructural analysis of its effects on feeding and other behaviour in the rat.

Behav. Pharmacol. 5 , 210-218 , (1994)

A-68930 [1R, 3S)-1-aminomethyl-5,6-dihydroxy-3-phenylisochroman HCI] is a novel, potent and selective dopamine D1 receptor agonist. Previous reports have shown that the selective D1 partial agonist, S...

Sedative effects of the dopamine D1 receptor agonist A 68930 on rat open-field behavior.

Neuroreport 11 , 1269-1279, (2000)

The present results demonstrate sedative effects of the DA D1 receptor agonist A 68930 (0.9-15 micromol kg(-1), s.c.) on rat spontaneous locomotor activity in an open field. The effects were particula...

A68930: a potent and specific agonist for the D-1 dopamine receptor.

Am. J. Hypertens. 3 , 40S-42S, (1990)

A68930 (5,6-dihydroxy-3-phenyl-1-aminomethyl-isochroman) is a potent (EC50 = 2.5 nmol/L) partial agonist at the D-1 dopamine receptor. In contrast, A68930 is a much weaker agonist (EC50 = 3,920 nmol/L...


More Articles


Related Compounds

  • A-68930 hydrochloride
  • WAY 207024 dihydrochloride
  • a-68930
  • (7S,9R,10R)-7,10-bis[[(2S,4S,5S,6S)-4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]oxy]-9-ethyl-4,6,9,11-tetrahydroxy-8,10-dihydro-7H-tetracene-5,12-dione,dihydrochloride
  • Mannostatin A, Hydrochloride
  • erythromycin-A, hydrochloride
  • Methyl 8-benzyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylate
  • Tert-butyl 2-[(propylamino)methyl]-7-azabicyclo[2.2.1]heptane-7-carboxylate
  • (2S)-2-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)heptanamido]hexanoic acid
  • 4-{2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)phenyl]acetamido}butanoic acid
  • 3-(N-ethyl-1-{5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolan-3-yl}formamido)-2-methylpropanoic acid
  • rac-(3R,4S)-1-[(benzyloxy)carbonyl]-4-(4-bromo-2-fluorophenyl)pyrrolidine-3-carboxylic acid
  • 2-[(2S)-1-[(3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoyl]pyrrolidin-2-yl]acetic acid
  • (2S,3S)-2-({5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolan-3-yl}formamido)-3-methylpentanoic acid
  • 4-[(3S)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)heptanamido]hexanoic acid
  • 2-{[(Benzyloxy)carbonyl]amino}-4-cyclobutylpentanoic acid
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