L-655,708

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Names

[ CAS No. ]:
130477-52-0

[ Name ]:
L-655,708

[Synonym ]:
l-655,708
L-655708

Chemical & Physical Properties

[ Density]:
1.42g/cm3

[ Boiling Point ]:
584.4ºC at 760mmHg

[ Molecular Formula ]:
C18H19N3O4

[ Molecular Weight ]:
341.36100

[ Flash Point ]:
307.2ºC

[ Exact Mass ]:
341.13800

[ PSA ]:
73.66000

[ LogP ]:
2.28620

[ Vapour Pressure ]:
1.21E-13mmHg at 25°C

[ Index of Refraction ]:
1.675

[ Storage condition ]:
2-8℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Rat and human hippocampal alpha5 subunit-containing gamma-aminobutyric AcidA receptors have alpha5 beta3 gamma2 pharmacological characteristics.

Mol. Pharmacol. 54 , 928-933, (1998)

The gamma-aminobutyric acid (GABA)A receptor is a hetero-oligomer consisting of five subunits, the combination of which confers unique pharmacological properties to the receptor. To understand the phy...

Autoradiographic localization of alpha5 subunit-containing GABAA receptors in rat brain.

Brain Res. 822 , 265-270

Multiple subtypes of GABAA receptors are expressed in the rat central nervous system (CNS). To determine the distribution and proportion of alpha5 subunit containing receptors, quantitative autoradiog...

Rapid Antidepressant Action and Restoration of Excitatory Synaptic Strength After Chronic Stress by Negative Modulators of Alpha5-Containing GABAA Receptors.

Neuropsychopharmacology 40 , 2499-509, (2015)

Selective serotonin reuptake inhibitors (SSRIs) are the primary pharmacological treatment for depression, but SSRIs are effective in only half of the patients and typically take several weeks to relie...


More Articles

Related Compounds

  • L-655,240
  • L-Malic acid dipotassium
  • L-Cysteine,S-(aminocarbonyl)-
  • L-Serine-13C3,15N
  • L-Leucyl-O-(2-acetamido-2-desoxy-α-D-galactopyranosyl)-L-serin
  • L-(+)-tartaric acid diammonium salt
  • N-(2-(1H-pyrazol-1-yl)-2-(thiophen-3-yl)ethyl)-4-propyl-1,2,3-thiadiazole-5-carboxamide
  • N-(2-(1H-pyrazol-1-yl)-2-(thiophen-3-yl)ethyl)-2-chloro-6-fluorobenzamide
  • 6-(1H-1,2,4-triazol-1-yl)-2-(2,2,2-trifluoroethyl)pyridazin-3(2H)-one
  • 6-(2-aminoethyl)-N-ethyl-N-methylpyridin-2-amine
  • 6-(2-aminoethyl)-N-cyclopropylpyridin-2-amine
  • 2-(6-(1H-pyrazol-1-yl)pyridin-2-yl)ethan-1-amine
  • 2-(6-(1H-1,2,4-triazol-1-yl)pyridin-2-yl)ethan-1-amine
  • 2-(6-(Benzyloxy)pyridin-2-yl)ethan-1-amine
  • 2-Phenyl-2-(pyrazin-2-yl)ethan-1-amine
  • 3-Methoxy-2-(6-methylpyridazin-3-yl)propan-1-amine
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