Hydroxylapatite

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Names

[ CAS No. ]:
1306-06-5

[ Name ]:
Hydroxylapatite

[Synonym ]:
Durapatite
Hydroxylapatite
Calcium phosphate hydroxide,Durapatite,Hydroxylapatite
Hydroxyapatite
Monite
MFCD00010904
Calcium hydroxide phosphate (5:1:3)
EINECS 215-145-7

Chemical & Physical Properties

[ Density]:
3.140 g/cm3

[ Boiling Point ]:
158ºC at 760 mmHg

[ Melting Point ]:
1100 °C(lit.)

[ Molecular Formula ]:
Ca2HO5P

[ Molecular Weight ]:
502.311

[ Exact Mass ]:
501.675964

[ PSA ]:
119.12000

[ LogP ]:
0.20920

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: 0.3 mg/mL, clear, colorless

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MY8434000
CHEMICAL NAME :
Hydroxylapatite (Ca5(OH)(PO4)3) (9CI)
CAS REGISTRY NUMBER :
1306-06-5
LAST UPDATED :
199806
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
Ca5-H-O13-P3
MOLECULAR WEIGHT :
502.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>25350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>19850 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>99500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>25500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>30 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Mammal - species unspecified Lymphocyte
DOSE/DURATION :
200 mg/L
REFERENCE :
IJBBBQ Indian Journal of Biochemistry and Biophysics. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.8- 1971- Volume(issue)/page/year: 19,71,1982

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MY8434000

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Related Compounds

  • HYDROXYLAPATITE
  • fluor-hydroxylapatite
  • Barium hydroxylapatite
  • Calcium hydroxyphosphate,HAp,Hydroxylapatite
  • 2,4,6-trifluoro-N,N-dimethylbenzamide
  • 5-(5-Methylthiophen-3-yl)furan-2-carboxylic acid
  • 5-(5-Methylthiophen-3-yl)thiophene-2-carboxylic acid
  • 3-(5-Methylthiophen-3-yl)thiophene-2-carboxylic acid
  • 4-Fluoro-3-(thiophen-3-yl)benzaldehyde
  • 2-Chloro-5-(5-methylthiophen-3-yl)benzoic acid
  • 2-(5-Methylthiophen-3-yl)benzaldehyde
  • 2-(3,3-Dimethylmorpholin-4-yl)acetonitrile
  • Ethyl 2-(3,3-dimethylmorpholin-4-yl)acetate
  • 2-(3,3-Dimethyl-4-morpholinyl)benzenemethanol
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