2,2',4,4'-Tetrahydroxybenzophenone

Suppliers

Names

[ CAS No. ]:
131-55-5

[ Name ]:
2,2',4,4'-Tetrahydroxybenzophenone

[Synonym ]:
Seesorb 106
70A-196
2,2',4,4'-Tetrahydroxybenzophenone
BENZOPHENONE-2
2,2',4,4'-Tetrahydroxybenzophe
EINECS 205-028-9
uvinuld-50
2,2′,4,4′-tetrahydroxybenzophenone
2,2',4,4'-tetrahyroxybenzophenone
2,4,2',4'-tetrahydroxybenzophenone
TETRAHYDROXYBENZOPHENONE
Methanone, bis(2,4-dihydroxyphenyl)-
Sumisorb 150
Bis(2,4-dihydroxyphenyl)methanone
Uvinol D-50
2,2',4,4'-tetrahydroxy-benzophenone
MFCD00002278

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
531.2±25.0 °C at 760 mmHg

[ Melting Point ]:
198-200 °C(lit.)

[ Molecular Formula ]:
C13H10O5

[ Molecular Weight ]:
246.215

[ Flash Point ]:
289.1±19.7 °C

[ Exact Mass ]:
246.052826

[ PSA ]:
97.99000

[ LogP ]:
3.16

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.718

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ1892000
CHEMICAL NAME :
Benzophenone, 2,2',4,4'-tetrahydroxy-
CAS REGISTRY NUMBER :
131-55-5
BEILSTEIN REFERENCE NO. :
1914746
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C13-H10-O5
MOLECULAR WEIGHT :
246.23
WISWESSER LINE NOTATION :
QR CQ DVR BQ DQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1220 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
200 ug/plate
REFERENCE :
JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 2(5),35,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7078 No. of Facilities: 9 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 869 (estimated) No. of Female Employees: 617 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
DJ1892000

[ Packaging Group ]:
II; III

[ Hazard Class ]:
4.1

[ HS Code ]:
2914501900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2,4-Dihydroxybenzoic acid
  • Resorcine
  • 2,2'-Dihydroxy-4,4'-dimethoxybenzophenone
  • 2 2' 4 4'-TETRAMETHOXYBENZOPHENONE
  • 1,2-Dichlorobenzene
  • N,N-Dimethylformamide
  • 1,3-Dimethoxybenzene

DownStream

  • 2,4,5,7-tetraiodo-6-hydroxy-3-fluorone
  • 2 2' 4 4'-TETRAMETHOXYBENZOPHENONE
  • 3,6-BIS[[(1,1-DIMETHYLETHYL)DIMETHYLSILYL]OXY]-9H-XANTHEN-9-ONE
  • 3-(2,4-dihydroxyphenyl)-1,2-dihydroindazol-6-one
  • 6-hydroxy-3-xanthen-3-one

Customs

[ HS Code ]: 2914501900

[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Selectivity of natural, synthetic and environmental estrogens for zebrafish estrogen receptors.

Toxicol. Appl. Pharmacol. 280(1) , 60-9, (2014)

Zebrafish, Danio rerio, is increasingly used as an animal model to study the effects of pharmaceuticals and environmental estrogens. As most of these estrogens have only been tested on human estrogen ...

Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity.

Toxicol. Appl. Pharmacol. 282(2) , 119-28, (2015)

Benzophenone-3 (2-hydroxy-4-methoxybenzophenone; BP-3) is widely used as sunscreen for protection of human skin and hair from damage by ultraviolet (UV) radiation. In this study, we examined the metab...

Ultra-preconcentration and determination of selected pharmaceutical and personal care products in different water matrices by solid-phase extraction combined with dispersive liquid-liquid microextraction prior to ultra high pressure liquid chromatography tandem mass spectrometry analysis.

J. Chromatogr. A. 1355 , 26-35, (2014)

Pharmaceutical and personal care products (PPCPs) are one of the most important classes of emerging contaminants. The potential of ecological and environmental impacts associated with PPCPs are of par...


More Articles

Related Compounds

  • 5,5'-difluoro-2,2',4,4'-tetrahydroxybenzophenone
  • 2,2',4,4'-tetrachlorodibenzyl ether
  • 2,2',4,4',6,6'-HEXABROMOBIPHENYL
  • 2,2',4,4',5,5'-hexabromodiphenyl ether
  • 2,2',4,4',6-pentakisbenzyloxy-3'-chloro-6'-methylbenzophenone
  • 2,2',4,4',5,5'-hexachloro-[1,1'-biphenyl]-3,3'-diamine