2-Naphthalenamine,1-[2-(2-methylphenyl)diazenyl]-

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Names

[ CAS No. ]:
131-79-3

[ Name ]:
2-Naphthalenamine,1-[2-(2-methylphenyl)diazenyl]-

[Synonym ]:
Yellow OB
Cerisol Yellow TB
Jaune OB
Oil Yellow OB
C.I. Solvent Yellow 6
C Yellow 4
Oil Yellow OB Pure
1-o-Tolylazo-[2]naphthylamin
C.I. Food Yellow 11
1-o-tolylazo-[2]naphthylamine
1-(2'-methylbenzeneazo)-2-amino-naphthalene
o-(2-amino-1-naphthylazo)toluene
FD and C Yellow No. 4
Dolkwal Yellow OB

Chemical & Physical Properties

[ Density]:
1.15g/cm3

[ Boiling Point ]:
478.7ºC at 760mmHg

[ Molecular Formula ]:
C17H15N3

[ Molecular Weight ]:
261.32100

[ Flash Point ]:
243.3ºC

[ Exact Mass ]:
261.12700

[ PSA ]:
50.74000

[ LogP ]:
5.72700

[ Vapour Pressure ]:
2.51E-09mmHg at 25°C

[ Index of Refraction ]:
1.636

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QM5400000
CHEMICAL NAME :
2-Naphthylamine, 1-(o-tolylazo)-
CAS REGISTRY NUMBER :
131-79-3
BEILSTEIN REFERENCE NO. :
0658385
LAST UPDATED :
199612
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C17-H15-N3
MOLECULAR WEIGHT :
261.35
WISWESSER LINE NOTATION :
L66J BNUNR B& CZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
120 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
36400 mg/kg/2Y-C
TOXIC EFFECTS :
Blood - changes in cell count (unspecified) Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
45625 mg/kg/1Y-C
TOXIC EFFECTS :
Related to Chronic Data - death
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
700 mg/kg/2Y-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
50 ug/plate
REFERENCE :
CANCAR Cancer (Philadelphia). (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1948- Volume(issue)/page/year: 49,1970,1982 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,287,1975 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 8,287,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW ARVPAX Annual Review of Pharmacology. (Palo Alto, CA) V.1-15, 1961-75. For publisher information, see ARPTDI. Volume(issue)/page/year: 14,127,1974 TOXICOLOGY REVIEW ZEKBAI Zeitschrift fuer Krebsforschung. (Berlin, Fed. Rep. Ger.) V.1-75, 1903-71. For publisher information, see JCROD7. Volume(issue)/page/year: 60,344,1955

Safety Information

[ HS Code ]:
2927000090

Precursor & DownStream

Precursor

  • o-Toluidine HCl
  • naphthalene-2-diazonium,chloride
  • Naphthalen-2-amine

DownStream

  • 2-Nitro-1-naphthol
  • naphthalene-1,2-diamine
  • o-Toluidine
  • C.I. Solvent Orange 2

Customs

[ HS Code ]: 2927000090

[ Summary ]:
2927000090 other diazo-, azo- or azoxy-compounds。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Related Compounds

  • 2-Thiazolamine,5-[2-(2-methylphenyl)diazenyl]-4-phenyl-
  • 2-Naphthalenamine,1,2,3,4-tetrahydro-N,N,2,4,4-pentamethyl-, hydrochloride (1:1)
  • 2-[1-Hydroxy-2-(2-methylphenyl)-ethyl]-cyclohexanol
  • 2-Pyrimidinamine,4-methyl-5-[2-(2-methylphenyl)diazenyl]-6-phenyl-
  • 2-[[1-(2-hydroxyphenyl)-3-(2-methylphenyl)-3-oxopropyl]amino]benzoic acid
  • 2-Naphthalenesulfonicacid,4-hydroxy-7-[[[[5-hydroxy-6-[2-(2-methylphenyl)diazenyl]-7-sulfo-2-naphthalenyl]amino]carbonyl]amino]-3-[2-(6-sulfo-2-naphthalenyl)diazenyl]-,sodium salt (1:3)