NVP-BKM120 (Hydrochloride)

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Names

[ CAS No. ]:
1312445-63-8

[ Name ]:
NVP-BKM120 (Hydrochloride)

[Synonym ]:
2-Pyridinamine, 5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-(trifluoromethyl)-, hydrochloride (1:1)
5-[2,6-Di(4-morpholinyl)-4-pyrimidinyl]-4-(trifluoromethyl)-2-pyridinamine hydrochloride (1:1)
NVP-BKM120 Hydrochloride
Buparlisib hydrochloride [USAN]
BKM 120 hydrochloride
5-(2,6-di-4-morpholinyl-4-pyrimidinyl)-4-trifluoromethylpyridin-2-amine monohydrochloride
BUPARLISIB HYDROCHLORIDE
BKM120-AAA
UNII-194LK4P5K1
5-(2,6-di-4-morpholinylpyrimidinyl)-4-(trifluoromethyl)pyridine-2-amine hydrochloride
Buparlisib HCl
NVP-BKM120 (Hydrochloride)

Chemical & Physical Properties

[ Molecular Formula ]:
C18H22ClF3N6O2

[ Molecular Weight ]:
446.854

[ Exact Mass ]:
446.144501

[ PSA ]:
90.36000

[ LogP ]:
2.67490

[ Storage condition ]:
2-8℃

Precursor & DownStream

Precursor

  • 4,4'-(6-chloropyriMidine-2,4-diyl)diMorpholine
  • 2-Amino-4-(trifluoromethyl)pyridine
  • 5-Bromo-4-(trifluoromethyl)pyridin-2-amine
  • 4,4'-[6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine-2,4-diyl]di[morpholine]

DownStream

Related Compounds

  • BKM120
  • NVP-MELK8a hydrochloride
  • NVP-BAG956
  • NVP-CLR457
  • NVP-DKY709
  • NVP-ADW742
  • tert-butyl (5Z)-5-(2-ethoxy-2-oxoethylidene)-2-azabicyclo[2.2.1]heptane-2-carboxylate
  • ethyl 2-[(3Z)-7-bromo-2,3-dihydro-1-benzofuran-3-ylidene]acetate
  • ethyl 2-[(4E)-7,8-dichloro-3,4-dihydro-2H-1-benzopyran-4-ylidene]acetate
  • 3-methyl-1-(oxolan-3-yl)-1H-pyrazole-4-carbonitrile
  • 1-(4,4-dimethylcyclohexyl)-3-methyl-1H-pyrazole-4-carbonitrile
  • 2-Methyl-6-[(pent-1-yn-3-yl)amino]pyrimidine-4-carboxylic acid
  • 3-methyl-1-(6-methylpyridin-2-yl)-1H-pyrazole-4-carbonitrile
  • 1-(3-hydroxy-2,2-dimethylpropyl)-3-methyl-1H-pyrazole-4-carbonitrile
  • 4-Bromo-5-(2-ethynylpyrrolidin-1-yl)furan-2-carboxylic acid
  • 6-[Cyclopropyl(prop-2-yn-1-yl)amino]pyridine-2-carboxylic acid
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