4,6-bis(aziridin-1-yl)-2,5-dichloropyrimidine

Names

[ CAS No. ]:
13150-18-0

[ Name ]:
4,6-bis(aziridin-1-yl)-2,5-dichloropyrimidine

[Synonym ]:
4,6-bis-aziridin-1-yl-2,5-dichloro-pyrimidine

Chemical & Physical Properties

[ Density]:
1.675g/cm3

[ Boiling Point ]:
472.9ºC at 760mmHg

[ Molecular Formula ]:
C8H8Cl2N4

[ Molecular Weight ]:
231.08200

[ Flash Point ]:
239.8ºC

[ Exact Mass ]:
230.01300

[ PSA ]:
31.80000

[ LogP ]:
1.55340

[ Vapour Pressure ]:
4.12E-09mmHg at 25°C

[ Index of Refraction ]:
1.715

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UV7072100
CHEMICAL NAME :
Pyrimidine, 4,6-bis(1-aziridinyl)-2,5-dichloro-
CAS REGISTRY NUMBER :
13150-18-0
BEILSTEIN REFERENCE NO. :
0656736
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H8-Cl2-N4
MOLECULAR WEIGHT :
231.10
WISWESSER LINE NOTATION :
T6N CNJ BG D- AT3NTJ& EG F- AT3NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10700 ug/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 5,101,1970
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 5,101,1970

Related Compounds

  • 4,6-bis(aziridin-1-yl)-2-methyl-5-nitropyrimidine
  • 4,6-bis(aziridin-1-yl)-2-(4-chlorophenyl)-5-nitropyrimidine
  • 4,6-bis(aziridin-1-yl)-2-naphthalen-2-yl-5-nitropyrimidine
  • 4,6-bis(aziridin-1-yl)-2-(4-methoxy-3-nitrophenyl)-5-nitropyrimidine
  • 4,6-bis(aziridin-1-yl)-2-naphthalen-2-ylpyrimidine
  • 4,6-bis(aziridin-1-yl)-2-phenylpyrimidine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • (S)-2-(4-Bromo-2-methylphenyl)pyrrolidine
  • 2-fluoro-2'-methylbiphenyl-4-yl Methyl Ether
  • [2-(1-Methoxyethyl)-1,3-thiazol-4-yl]methanamine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 3-[2-(Trifluoromethyl)phenyl]butan-2-one
  • 2-Amino-4,5-dimethyl-4,5,6,7-tetrahydro-1-benzothiophene-3-carbonitrile
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol