2-Nitroso-1-naphthol

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Names

[ CAS No. ]:
132-53-6

[ Name ]:
2-Nitroso-1-naphthol

[Synonym ]:
C.I.Oxidation Base 15
2-nitroso-1-naphtho
1-Naphthalenol, 2-nitroso-
EINECS 205-064-5
2-Nitrosonaphthol
1-hydroxy-2-nitrosonaphthalene
2-Nitroso-1-naphthol
1-Naphthol,2-nitroso
2-nitrosonaphthalen-1-ol
2-Nitroiso-1-Naphthol
nitrosonaphthol
MFCD00003932
2-nitroso-1-hydroxy-naphthalene

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
357.6±25.0 °C at 760 mmHg

[ Melting Point ]:
150-155 °C (dec.)(lit.)

[ Molecular Formula ]:
C10H7NO2

[ Molecular Weight ]:
173.168

[ Flash Point ]:
170.1±23.2 °C

[ Exact Mass ]:
173.047684

[ PSA ]:
49.66000

[ LogP ]:
2.42

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.630

[ Water Solubility ]:
SLIGHTLY SOLUBLE

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QL4550000
CHEMICAL NAME :
1-Naphthol, 2-nitroso-
CAS REGISTRY NUMBER :
132-53-6
BEILSTEIN REFERENCE NO. :
1867919
LAST UPDATED :
199710
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H7-N-O2
MOLECULAR WEIGHT :
173.18
WISWESSER LINE NOTATION :
L66J BQ CNO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,35,1953 ** TUMORIGENIC DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
31 gm/kg/1Y-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Reproductive - Tumorigenic effects - testicular tumors
REFERENCE :
JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 41,985,1968

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
QL4550000

[ HS Code ]:
2908999090

Synthetic Route

Customs

[ HS Code ]: 2908999090

[ Summary ]:
2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Oxidative DNA damage induced by a metabolite of 2-naphthylamine, a smoking-related bladder carcinogen.

Jpn. J. Cancer Res. 93 , 736-743, (2002)

2-Naphthylamine (2-NA), a bladder carcinogen, is contained in cigarette smoke. DNA adduct formation is thought to be a major cause of DNA damage by carcinogenic aromatic amines. We have investigated w...

2-Nitroso-1-naphthol as a selective reagent for preconcentration of cobalt by vortex assisted combined with solidification of organic droplet and its determination by flame atomic absorption spectrometry.

Environ. Monit. Assess. 185(11) , 9067-75, (2013)

Highly rapid and selective vortex-assisted liquid-liquid microextraction based on solidification of organic drop has been used for determination of cobalt ion. 2-Nitroso-1-naphthol (2N1N) was used as ...

Separation, preconcentration and inductively coupled plasma-mass spectrometric (ICP-MS) determination of thorium(IV), titanium(IV), iron(III), lead(II) and chromium(III) on 2-nitroso-1-naphthol impregnated MCI GEL CHP20P resin.

J. Hazard. Mater. 173(1-3) , 669-74, (2010)

A simple and effective method is presented for the separation and preconcentration of Th(IV), Ti(IV), Fe(III), Pb(II) and Cr(III) by solid phase extraction on 2-nitroso-1-naphthol impregnated MCI GEL ...


More Articles


Related Compounds

  • 2-nitroso-1-naphthol
  • 7-chloro-2-nitroso-1-naphthol
  • 2-Nitroso-1-naphthol-5-sulfonicacid
  • 2-nitroso-1-naphthol-4-sulfonic acid
  • 2-nitroso-1-naphthol-4-sulphonic acid
  • 2-Nitroso-1-naphthol-4-sulfonsaeure Natriumsalz
  • exo-cis-(+/-)-1-(N-acetylmethyl)-7-oxabicyclo[2.2.1]hept-5-en-2,3-dicarboxylic anhydride
  • 2-[1-(Aminomethyl)-3-methylcyclopentyl]-2-hydroxyacetic acid
  • N-(6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-1-yl)-4-phenyltetrahydro-2H-pyran-4-carboxamide
  • 1,3-Dihydro-3-(2-piperidinylmethylene)-2H-indol-2-one
  • I(2)-[(4-Butoxyphenyl)methylene]-I+/--(1,1-dimethylethyl)-1H-1,2,4-triazole-1-ethanol
  • 3-(Aminomethyl)-1,1-dimethoxy-3-methylpentan-2-ol
  • 2H-Azeto[1,2-a]cyclopenta[c]pyrrole-4-carboxylic acid, 1,5,6,7,7a,7b-hexahydro-1-[(1R)-1-hydroxyethyl]-2-oxo-, (1S,7aR,7bR)-
  • 4-Cyclopropoxy-3-sulfamoylpicolinamide
  • 2-(6-fluoro-2-methyl-4-oxoquinazolin-3(4H)-yl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)acetamide
  • 3-Cyclopropoxy-4-sulfamoylpicolinamide
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