[1-butoxy-3-(5-ethyl-2,4,6-trioxo-5-phenyl-1,3-diazinan-1-yl)propan-2-yl] carbamate

Names

[ CAS No. ]:
13246-02-1

[ Name ]:
[1-butoxy-3-(5-ethyl-2,4,6-trioxo-5-phenyl-1,3-diazinan-1-yl)propan-2-yl] carbamate

[Synonym ]:
Febarbamato [INN-Spanish]
Phebarbamate
G-Tril
EINECS 236-226-3
Getril
Febarbamatum [INN-Latin]
1-(3-butoxy-2-carbamoyloxy-propyl)-5-ethyl-5-phenyl-pyrimidine-2,4,6-trione
Febarbamate
N-(2-carbamoyloxy-3-butoxypropyl) phenobarbital
Solium
1-<3-Butyloxy-2-carbamoyloxy-propyl>-5-ethyl-5-phenyl-barbitursaeure
phenobamate
Tymium
1-(3-n-butoxy-2-carbamoyloxypropyl)-5-ethyl-5-phenyl-(1H,3H,5H) pyrimidine-2,4,6-trione

Chemical & Physical Properties

[ Density]:
1.214g/cm3

[ Molecular Formula ]:
C20H27N3O6

[ Molecular Weight ]:
405.44500

[ Exact Mass ]:
405.19000

[ PSA ]:
128.03000

[ LogP ]:
2.66040

[ Index of Refraction ]:
1.532

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CQ1480000
CHEMICAL NAME :
Barbituric acid, 1-(3-butoxy-2-hydroxypropyl)-5-ethyl-5-phenyl-, carbamate (ester)
CAS REGISTRY NUMBER :
13246-02-1
BEILSTEIN REFERENCE NO. :
0591584
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H27-N3-O6
MOLECULAR WEIGHT :
405.50
WISWESSER LINE NOTATION :
T6VMVNV FHJ D1YOVZ1O4 F2 FR

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1065 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HPPAAL Helvetica Physiologia et Pharmacologica Acta. (Basel, Switzerland) V.1-26, 1943-68. Discontinued. Volume(issue)/page/year: 19,241,1961

Precursor & DownStream

Precursor

  • PHOSPHORISOCYANATIDIC DICHLORIDE
  • 1-(3-butoxy-2-hydroxy-propyl)-5-ethyl-5-phenyl-pyrimidine-2,4,6-trione
  • Chlorosulfonylisocyanate
  • 1-chloro-3-butoxy-2-carbamoyloxypropane
  • phenobarbital sodium

DownStream

Related Compounds

  • 3-{[(Benzyloxy)carbonyl]amino}-4-phenylthiophene-2-carboxylic acid
  • 2-Methyl-2-(pyrimidin-5-yl)propan-1-ol
  • (5,5-Dimethyl-1,4-dioxan-2-yl)methanesulfonamide
  • [2-(Trifluoromethyl)spiro[3.3]heptan-2-yl]methanesulfonamide
  • tert-butyl (6R)-2,2-dimethyl-6-(sulfamoylmethyl)morpholine-4-carboxylate
  • 1-Benzyl-2-(but-3-yn-1-yl)pyrrolidine
  • rac-tert-butyl N-[(1R,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-N-methylcarbamate
  • tert-butyl N-[2-(4-hydroxyphenyl)-2-methoxyethyl]carbamate
  • tert-butyl N-[(1S)-2,2,2-trifluoro-1-(2-fluoro-4-hydroxyphenyl)ethyl]carbamate
  • Tert-butyl (2s,4s)-2-hydroxy-2-(trifluoromethyl)-8-oxa-5-azaspiro[3.5]nonane-5-carboxylate