(2S,4S)-DIBENZYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE

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Names

[ Name ]:
(2S,4S)-DIBENZYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE

[Synonym ]:
(2S,4S)-dibenzyl4-hydroxypyrrolidine-1,2-dicarboxylate
(2S,4S)-4-hydroxy-1,2-pyrrolidinedicarboxylic acid 1,2-bis(phenylmethyl ester)

Chemical & Physical Properties

[ Density]:
1.3 g/cm3

[ Boiling Point ]:
517.884ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₁NO₅

[ Molecular Weight ]:
355.38400

[ Flash Point ]:
267.007ºC

[ Exact Mass ]:
355.14200

[ PSA ]:
76.07000

[ LogP ]:
2.43970

[ Index of Refraction ]:
1.608

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(2S,4R)-DIBENZYL 4-HYDROXYPYRROLIDINE-1,2-DICARBOXYLATE
N-(Benzyloxycarbonyloxy)succinimide
(2S,4S)-4-(formyloxy)-1,2-pyrrolidinedicarboxylic acid 1,2-bis(phenylmethyl ester)
Benzyl chloroformate
L-Hydroxyproline
Z-Hyp-OH
(2S,4S)-dibenzyl 4-((4-nitrobenzoyl)oxy)pyrrolidine-1,2-dicarboxylate

DownStream

cis-4-hydroxy-L-proline
(4S)-1-[(Benzyloxy)carbonyl]-4-hydroxy-L-proline

Related Compounds

4-[3-(Fluoromethyl)piperidine-1-carbonyl]-1-phenylpyrrolidin-2-one
4-(Fluoromethyl)-1-(1-phenylcyclopropanecarbonyl)piperidine
2-ethoxy-1-(5-{2-methyl-5H,6H,7H-cyclopenta[d]pyrimidin-4-yl}-octahydropyrrolo[3,4-c]pyrrol-2-yl)ethan-1-one
1-[(5-Chlorothiophen-2-yl)sulfonyl]-4-(fluoromethyl)piperidine
4-[4-(Fluoromethyl)piperidine-1-carbonyl]-1-(3-methoxyphenyl)pyrrolidin-2-one
6-{[4-(Fluoromethyl)piperidin-1-yl]sulfonyl}-1,2,3,4-tetrahydroquinolin-2-one
4-(Fluoromethyl)-1-[1-(4-fluorophenyl)cyclopropanecarbonyl]piperidine
N-cyclobutyl-1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazole-4-carboxamide
4-[3-(3,4,5-trimethyl-1H-pyrazol-1-yl)pyrazin-2-yl]morpholine
1-[(5-Bromothiophen-2-yl)sulfonyl]-4-(fluoromethyl)piperidine

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