(2S,4S)-4-Amino-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl) ester

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Names

[ CAS No. ]:
132622-66-3

[ Name ]:
(2S,4S)-4-Amino-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl) ester

[Synonym ]:
(2S,4S)-4-amino-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
(2S,4S)-4-Amino-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl) ester

Chemical & Physical Properties

[ Density]:
1.232g/cm3

[ Boiling Point ]:
371.1ºC at 760mmHg

[ Melting Point ]:
>266ºC(lit.)

[ Molecular Formula ]:
C10H18N2O4

[ Molecular Weight ]:
230.26100

[ Flash Point ]:
178.2ºC

[ Exact Mass ]:
230.12700

[ PSA ]:
92.86000

[ LogP ]:
1.04590

[ Vapour Pressure ]:
1.59E-06mmHg at 25°C

[ Index of Refraction ]:
1.516

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (2S,4S)-1-(tert-Butoxycarbonyl)-4-azidopyrrolidine-2-carboxylic acid
  • (2S,4S)-1-tert-Butyl 2-methyl 4-aminopyrrolidine-1,2-dicarboxylate
  • N-Boc-cis-4-Fmoc-Amino-L-proline
  • (2S,4R)-1-(tert-butoxycarbonyl)-4-[(methylsulfonyl)oxy]proline benzyl ester
  • boc-hyp-obzl

DownStream

  • N-Boc-cis-4-Fmoc-Amino-L-proline