1-[(2R,3S,4S,5R)-3-azido-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Names

[ CAS No. ]:
132776-27-3

[ Name ]:
1-[(2R,3S,4S,5R)-3-azido-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

[Synonym ]:
AZdd-3'-F-methyl-U
2'-azido-3'-fluoro-2',3'-dideoxythymidine
2'-azido-2',3'-dideoxy-3'-fluoro-5-methyluridine

Chemical & Physical Properties

[ Molecular Formula ]:
C10H12FN5O4

[ Molecular Weight ]:
285.23200

[ Exact Mass ]:
285.08700

[ PSA ]:
134.33000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • methyl 5-O-benzyl-3-fluoro-3-deoxy-β-D-arabino-furanoside
  • methyl 5-O-benzyl-2-O-tosyl-3-fluoro-3-deoxy-β-D-arabino-furanoside
  • 1-[(2R,3S,4S,5R)-3-azido-4-fluoro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • methyl 2-O-tosyl-3-fluorodeoxy-β-D-arabinofuranoside
  • methyl 3-deoxy-5-O-benzoyl-3-fluoro-2-O-tosyl-β-D-arabinofuranoside
  • 5-methyl-1-[(2R,4R)-4-(trityloxymethyl)-3,6-dioxabicyclo[3.1.0]hexan-2-yl]pyrimidine-2,4-dione
  • 1-[(2R,3R,4R,5R)-3-azido-4-hydroxy-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
  • [(2R,3R,4R,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-4-methylsulfonyloxy-2-(trityloxymethyl)oxolan-3-yl] methanesulfonate
  • 5-Methyluridine

DownStream

Related Compounds

  • 2-(3-Amino-5-hydroxyphenyl)-2,2-difluoroacetic acid
  • Hydroxy-PEG1-acid sodium salt
  • 5-Bromo-6-(2-fluoropropan-2-yl)pyridin-2-amine
  • 2-Amino-7-methyl-7,8-dihydro-5H-pyrano[4,3-b]pyridin-5-one
  • N-Fmoc-L-HomoPhe(3-I)-OH
  • 2-[N-(1-methoxypropan-2-yl)acetamido]acetic acid
  • 1-(5-Bromo-2-nitrophenyl)hydrazine hydrochloride
  • 5-Acetamido-1,2-oxazole-3-carboxylic acid
  • 5-(Piperidin-2-yl)-2-(trifluoromethyl)benzamide hydrochloride
  • 2-Methyl-5-(prop-1-yn-1-yl)pyrimidine-4-carboxylic acid
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