1-[(2R,3S,4S,5R)-3-azido-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Names

[ Name ]:
1-[(2R,3S,4S,5R)-3-azido-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione

[Synonym ]:
AZdd-3'-F-methyl-U
2'-azido-3'-fluoro-2',3'-dideoxythymidine
2'-azido-2',3'-dideoxy-3'-fluoro-5-methyluridine

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₁₂FN₅O₄

[ Molecular Weight ]:
285.23200

[ Exact Mass ]:
285.08700

[ PSA ]:
134.33000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

methyl 5-O-benzyl-3-fluoro-3-deoxy-β-D-arabino-furanoside
methyl 5-O-benzyl-2-O-tosyl-3-fluoro-3-deoxy-β-D-arabino-furanoside
1-[(2R,3S,4S,5R)-3-azido-4-fluoro-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
methyl 2-O-tosyl-3-fluorodeoxy-β-D-arabinofuranoside
methyl 3-deoxy-5-O-benzoyl-3-fluoro-2-O-tosyl-β-D-arabinofuranoside
5-methyl-1-[(2R,4R)-4-(trityloxymethyl)-3,6-dioxabicyclo[3.1.0]hexan-2-yl]pyrimidine-2,4-dione
1-[(2R,3R,4R,5R)-3-azido-4-hydroxy-5-(trityloxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
[(2R,3R,4R,5R)-5-(5-methyl-2,4-dioxopyrimidin-1-yl)-4-methylsulfonyloxy-2-(trityloxymethyl)oxolan-3-yl] methanesulfonate
5-Methyluridine

DownStream

Related Compounds

2-(Cyclobutylmethyl)pyrrolidine
2-[(4,7-Dimethylquinazolin-2-yl)amino]-6-(3-methylbutyl)-1,3-diazinan-4-one
2-Chloro-3-cyclopropoxy-N-methylbenzamide
N-[(4-Aminopyrimidin-2-yl)methyl]-5-(furan-2-yl)-1,2-oxazole-3-carboxamide
2-Amino-3-iodo-5-nitrophenol
N-(2,2-dimethylpropyl)-N-methylcarbamoyl chloride
4-Isopropyl-3-(methylthio)phenol
3-(5-Methylpyridin-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid
5-(Cyclohexylmethyl)-2-hydroxybenzamide
5-Cyclopropoxy-N-methyl-6-nitropicolinamide

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