PD 81,723

Names

[ Name ]:
PD 81,723

[Synonym ]:
(2-Amino-4,5-dimethylthiophen-3-yl)(3-(trifluoromethyl)phenyl)methanone
Tocris-1363
PD-81,723
(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone

Chemical & Physical Properties

[ Density]:
1.328g/cm3

[ Boiling Point ]:
411.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₄H₁₂F₃NOS

[ Molecular Weight ]:
299.31100

[ Flash Point ]:
202.8ºC

[ Exact Mass ]:
299.05900

[ PSA ]:
71.33000

[ LogP ]:
4.77810

[ Vapour Pressure ]:
5.48E-07mmHg at 25°C

[ Index of Refraction ]:
1.563

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.

J. Mol. Cell. Cardiol. 31(1) , 123-34, (1999)

The aim of this study was to determine whether endogenous adenosine has antiarrhythmic effects on ischemia-induced ventricular tachyarrhythmias. We therefore modulated the effect of endogenous adenosi...

A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury.

Am. J. Physiol. Renal Physiol. 303(5) , F721-32, (2012)

Activation of A(1) adenosine receptors (ARs) protects against renal ischemia-reperfusion (I/R) injury by reducing necrosis, apoptosis, and inflammation. However, extrarenal side effects (bradycardia, ...

Novel mitogenic effect of adenosine on coronary artery smooth muscle cells: role for the A1 adenosine receptor.

Circ. Res. 96(9) , 982-90, (2005)

Adenosine is a vascular endothelial cell mitogen, but anti-mitogenic for aortic smooth muscle cells and fibroblasts when acting via the A2B adenosine receptor. However, we show that adenosine increase...

PD 169316
PD 168568 dihydrochloride
PD 166793
PD-1/PD-L1 Inhibitor 3
[Pd(1,2-bis(diphenylphosphino)benzene)(4-chlorophenyl)(CH2C(O)C6H4-4-t-Bu)]
[Pd(1,2-bis(diphenylphosphino)benzene)(phenyl)(CH2C(O)C6H4-4-t-Bu)]
N-(2-(4-(cyclopropanecarboxamido)benzamido)ethyl)-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine-3-carboxamide
N-(3,4-dichlorophenyl)-6-methyl-4-oxo-4,5-dihydro[1,2,3]triazolo[1,5-a]pyrazine-3-carboxamide
6-methyl-3-[(4-phenylpiperazin-1-yl)carbonyl][1,2,3]triazolo[1,5-a]pyrazin-4(5H)-one
1-{[1-(2-fluorophenyl)-1H-1,2,3-triazol-5-yl]methyl}-4-[(2-methoxyphenyl)acetyl]piperazine
1-(3-chlorobenzyl)-4-((1-(2-methoxyphenyl)-1H-1,2,3-triazol-5-yl)methyl)piperazine
(4-((1-(3-fluoro-4-methoxyphenyl)-1H-1,2,3-triazol-5-yl)methyl)piperazin-1-yl)(1H-indol-5-yl)methanone
N-(3-chloro-4-fluorophenyl)-1-(2-hydroxy-2-phenylethyl)-1H-1,2,3-triazole-4-carboxamide
N-(3,5-difluorobenzyl)-1-[2-hydroxy-2-(2-methoxyphenyl)ethyl]-1H-1,2,3-triazole-4-carboxamide
N-(2-chlorophenyl)-2-(4-((4-(2-methoxyphenyl)-4H-1,2,4-triazol-3-yl)methyl)piperazin-1-yl)acetamide
Tert-butyl 3-[(1,3-thiazol-2-yl)amino]-8-azabicyclo[3.2.1]octane-8-carboxylate

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