Meglumine antimonate

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Names

[ CAS No. ]:
133-51-7

[ Name ]:
Meglumine antimonate

[Synonym ]:
Methylglucamine antimonate
2168-rp
Protostib {Antimonate}
D-Glucitol, 1-deoxy-1-(methylamino)-, compd. with trihydroxystibine, oxide (1:1)
glucantime
D-Glucitol, 1-deoxy-1-(methylamino)-, compd. with antimonic acid (1:1)
RP 2168 {Antimonate}
protostib
MFCD01725422
Antimonic acid - 1-deoxy-1-(methylamino)-D-glucitol (1:1)
N-Methylglucamine antimonate
N-METHYL GLUCAMINE ANTIMONATE
N-MethylgluamineAntimoniate
meglumineantimonate
Meglumine antimonate
MEGLUMINANTIMONIATE
EINECS 205-108-3
methylglucamineantimonate

Chemical & Physical Properties

[ Density]:
1.375g/cm3

[ Boiling Point ]:
490.4ºC at 760mmHg

[ Melting Point ]:
168-170°C

[ Molecular Formula ]:
C7H18NO8Sb

[ Molecular Weight ]:
383.995

[ Flash Point ]:
251.6ºC

[ Exact Mass ]:
383.017639

[ PSA ]:
167.55000

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ4370000
CHEMICAL NAME :
D-Glucitol, 1-deoxy-1-(methylamino)-, trioxoantimonate(1-)
CAS REGISTRY NUMBER :
133-51-7
LAST UPDATED :
199606
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H17-N-O5.H-O3-Sb
MOLECULAR WEIGHT :
366.01

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Unreported
SPECIES OBSERVED :
Human - child
DOSE/DURATION :
700 mg/kg/7D
TOXIC EFFECTS :
Kidney, Ureter, Bladder - interstitial nephritis Kidney, Ureter, Bladder - urine volume increased Kidney, Ureter, Bladder - urine volume decreased
REFERENCE :
MAMEA2 Maroc Medical. (Casablanca, Morocco) V.1-55, 1921-75. Discontinued. Volume(issue)/page/year: 41,1180,1962 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
27056 mg/kg/30D-I
TOXIC EFFECTS :
Blood - changes in leukocyte (WBC) count Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
REFERENCE :
HETOEA Human & Experimental Toxicology. (Macmillan Press Ltd., Brunel Road, Houndmills, Basingstoke, Hampshire, RG21 2XS, UK) V.9- 1990- Volume(issue)/page/year: 11,283,1992

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .

[ Safety Phrases ]:
S26-S36/37/39

Related Compounds

  • 3-acetamido-2,4,6-triiodo-5-[[2-(methylamino)-2-oxoethyl]carbamoyl]benzoic acid,(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
  • meglumine
  • meglumine cyclic adenylate
  • potassium antimonate
  • Lead antimonate
  • trisodium antimonate(3-)
  • 4-[[[1-(1,3-Dimethyl-1H-pyrazol-4-yl)ethyl]amino]carbonyl]-1H-pyrazole-1-acetic acid
  • 1-(4-Chlorophenyl)-1,4-dihydro-5-methoxy-4-oxo-3-cinnolinecarboxylic acid
  • 3-(4-Methyl-1H-imidazol-1-yl)benzenamine
  • Ethyl 1-(4-fluorophenyl)-4-(((4-methoxyphenyl)sulfonyl)oxy)-6-oxo-1,6-dihydropyridazine-3-carboxylate
  • O-(4-Fluorophenyl)homoserine
  • (4-Methyl-2,3-dihydrochromen-4-yl)methanol
  • 5-((4-(5-methyl-1H-benzo[d]imidazol-2-yl)phenyl)amino)-5-oxopentanoic acid
  • 2-(4-Carboxy-1-piperidylmethyl)propenenitrile
  • 1-Heptanol, 7,7,7-trichloro-, 1-acetate
  • N-(4-Amino-2-methylphenyl)-2-thiophenesulfonamide