L(+)-Amethopterin hydrate

Suppliers

Names

[ CAS No. ]:
133073-73-1

[ Name ]:
L(+)-Amethopterin hydrate

[Synonym ]:
MFCD00150848
L-Amethopterin hydrate
Methotrexate Hydrate

Chemical & Physical Properties

[ Density]:
1.536g/cm3

[ Melting Point ]:
195ºC

[ Molecular Formula ]:
C20H22N8O5

[ Molecular Weight ]:
454.43900

[ Exact Mass ]:
454.17100

[ PSA ]:
210.54000

[ LogP ]:
1.82170

[ Vapour Pressure ]:
0mmHg at 25°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H319-H360

[ Precautionary Statements ]:
P201-P301 + P310-P305 + P351 + P338-P308 + P313

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T

[ Risk Phrases ]:
61-25-36/38

[ Safety Phrases ]:
S26-S45-S53-S36-S37

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
MA1225000

Articles

Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells.

Br. J. Cancer 111(5) , 874-82, (2014)

Standard therapy for acute promyelocytic leukaemia (APL) includes retinoic acid (all-trans retinoic acid (ATRA)), which promotes differentiation of promyelocytic blasts. Although co-administration of ...

Cleavage efficient 2A peptides for high level monoclonal antibody expression in CHO cells.

MAbs 7(2) , 403-12, (2015)

Linking the heavy chain (HC) and light chain (LC) genes required for monoclonal antibodies (mAb) production on a single cassette using 2A peptides allows control of LC and HC ratio and reduces non-exp...

TLR signaling modulates side effects of anticancer therapy in the small intestine.

J. Immunol. 194(4) , 1983-95, (2015)

Intestinal mucositis represents the most common complication of intensive chemotherapy, which has a severe adverse impact on quality of life of cancer patients. However, the precise pathophysiology re...


More Articles

Related Compounds

  • L(+)-2-Amino-6-phosphonohexanoic acid hydrate
  • L(+)-Lysine monohydrate
  • l-(+)-canavanine sulfate monohydrate 9&
  • L(+)-Monosodium glutamate monohydrate
  • L-(+)Sodium glutamate
  • L-(+)-hernovine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine