1-(4-Iodophenyl)ethanone

Names

[ CAS No. ]:
13329-40-3

[ Name ]:
1-(4-Iodophenyl)ethanone

[Synonym ]:
MFCD00045320
EINECS 236-372-8
4‘-Iodoacetophenone
1-(4-Iodophenyl)ethanone
4’-Iodoacetophenone

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
279.9±23.0 °C at 760 mmHg

[ Melting Point ]:
82-84 °C(lit.)

[ Molecular Formula ]:
C₈H₇IO

[ Molecular Weight ]:
246.045

[ Flash Point ]:
123.1±22.6 °C

[ Exact Mass ]:
245.954147

[ PSA ]:
17.07000

[ LogP ]:
2.87

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.604

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29147090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-Acetylphenylboronic acid
Iodobenzene
1-Nitro-4-phenylethynyl-benzene
2-trimethylsilylphenyl triflate
4-Aminoacetophenone
1-(4-Bromophenyl)ethanone
1-(p-acetophenyl)-3,3-diethyl-1-triazene
carbon monoxide
Tetramethyltin
4-Iodobenzenediazonium tetrafluoroborate

DownStream

p-Hexylacetophenone
2-Bromo-4'-iodoacetophenone
2,2-dibromo-1-(4-iodophenyl)ethanone
4-Diethylaminoacetophenone
1-(4'-Methyl-4-biphenylyl)ethanone
BI-P-TOLYL
4,4'-Diacetylbiphenyl
1-(4-(4-methylbenzoyl)phenyl)ethan-1-one
4-(4-Iodophenyl)thiazol-2-ylamine
p-Butylacetophenone

Customs

[ HS Code ]: 29147090

Articles

Potential antitumor agents. 57. 2-Phenylquinoline-8-carboxamides as "minimal" DNA-intercalating antitumor agents with in vivo solid tumor activity.

J. Med. Chem. 32 , 396, (1989)

A series of phenyl-substituted derivatives of the "minimal" DNA-intercalating agent N-[2-(dimethylamino)-ethyl]-2-phenylquinoline-8-carboxamide (1) have been synthesized and evaluated for in vivo anti...

Sequential ring-closing metathesis and silicon-assisted cross-coupling reactions: stereocontrolled synthesis of highly substituted unsaturated alcohols.

Org. Lett. 3(11) , 1749-52, (2001)

A sequential ring-closing metathesis/silicon-assisted cross-coupling sequence has been developed. Alkenyldimethylsilyl ethers of omega-unsaturated alcohols undergo facile ring closure with Schrock's c...

Polyionic polymers--heterogeneous media for metal nanoparticles as catalyst in Suzuki-Miyaura and Heck-Mizoroki reactions under flow conditions.

Beilstein J. Org. Chem. 5 , 21, (2009)

The preparation of monolithic polyionic supports which serve as efficient heterogeneous supports for palladium(0) nanoparticles is described. These functionalized polymers were incorporated inside a f...