MG-132

Suppliers

Names

[ Name ]:
MG-132

[Synonym ]:
benzyloxycarbonyl-Leu-Leu-Leu-aldehyde
L-Leucinamide, N-((phenylmethoxy)carbonyl)-L-leucyl-N-((1S)-1-formyl-3-methylbutyl)-
Z-LLL-CHO
benzyl N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamate
MG132
zLLL
Z-Leu-Leu-Leu-CHO
Cbz-Leu-Leu-Leu-H
L-Leucinamide, N-[(phenylmethoxy)carbonyl]-L-leucyl-N-[(1S)-1-formyl-3-methylbutyl]-
N-[(Benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxopentan-2-yl]-L-leucinamide
Z-Leu-Leu-Leu-H
benzyloxycarbonylleucyl-leucyl-leucine aldehyde
benzyloxycarbonyl-leucyl-leucyl-leucinal
Z-Leu-Leu-leucinal
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal
MFCD00674886
Carbobenzoxy-L-leucyl-L-leucyl-L-leucinal
Cbz-Leu-Leu-Leu-CHO
N-[(Benzyloxy)carbonyl]-L-leucyl-N-[(2S)-4-methyl-1-oxo-2-pentanyl]-L-leucinamide
MG-132

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
682.0±55.0 °C at 760 mmHg

[ Melting Point ]:
80-84℃ (DEC.)

[ Molecular Formula ]:
C₂₆H₄₁N₃O₅

[ Molecular Weight ]:
475.621

[ Flash Point ]:
366.3±31.5 °C

[ Exact Mass ]:
475.304626

[ PSA ]:
113.60000

[ LogP ]:
5.75

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.506

[ Storage condition ]:
−20°C

[ Water Solubility ]:
methanol: 1 mg/mL | Soluble in ethanol, chloroform, methanol, water.

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

miR-1236 down-regulates alpha-fetoprotein, thus causing PTEN accumulation, which inhibits the PI3K/Akt pathway and malignant phenotype in hepatoma cells.

Oncotarget 6(8) , 6014-28, (2015)

Alpha fetoprotein (AFP) is a clinical biomarker of hepatocellular carcinoma (HCC). Here, we found that miR-1236 is down-regulated, whereas AFP is highly expressed in HCC tissues and cells. We demonstr...

Dominant negative effect of polyglutamine expansion perturbs normal function of ataxin-3 in neuronal cells.

Hum. Mol. Genet. 24(1) , 100-17, (2014)

The physiological function of Ataxin-3 (ATXN3), a deubiquitylase (DUB) involved in Machado-Joseph Disease (MJD), remains elusive. In this study, we demonstrate that ATXN3 is required for neuronal diff...

Hypoxia reduces MAX expression in endothelial cells by unproductive splicing.

FEBS Lett. 588(24) , 4784-90, (2014)

The MYC-MAX-MXD network is involved in the regulation of cell differentiation and proliferation. Hypoxia affects the expression levels of several members of this network, but changes specific to MAX e...