PROSTAGLANDIN A2
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Names
[ CAS No. ]:
13345-50-1
[ Name ]:
PROSTAGLANDIN A2
[Synonym ]:
PROSTAGLANDINS A2
Prostaglandin A
Prosta-5,10,13-trien-1-oic acid, 15-hydroxy-9-oxo-, (5E,13E,15S)-
Prostaglandin A2 solution
(5E,13E,15S)-15-Hydroxy-9-oxoprosta-5,10,13-trien-1-oic acid
Prostaglandin A2
MFCD00077859
PGA2
MEDULLIN
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
515.3±50.0 °C at 760 mmHg
[ Molecular Formula ]:
C20H30O4
[ Molecular Weight ]:
334.450
[ Flash Point ]:
279.6±26.6 °C
[ Exact Mass ]:
334.214417
[ PSA ]:
74.60000
[ LogP ]:
3.25
[ Vapour Pressure ]:
0.0±3.0 mmHg at 25°C
[ Index of Refraction ]:
1.555
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UK8050000
- CHEMICAL NAME :
- Prostaglandin A(sup 2)
- CAS REGISTRY NUMBER :
- 13345-50-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C20-H30-O4
- MOLECULAR WEIGHT :
- 334.50
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 93 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,460,1973 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 5 mg/kg
- SEX/DURATION :
- female 16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 1,191,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 10 mg/kg
- SEX/DURATION :
- female 16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - abortion
- REFERENCE :
- PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 1,191,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 10 mg/kg
- SEX/DURATION :
- female 16 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- PRGLBA Prostaglandins. (Geron-X, Inc., P.O. Box 1108, Los Altos, CA 94022) V.1- 1972- Volume(issue)/page/year: 2,295,1972 *** REVIEWS *** TOXICOLOGY REVIEW CSPEAX Cosmetics and Perfumery. (Oak Park, IL) V.88-90, 1973-75. For publisher information, see CTOIDG. Volume(issue)/page/year: 90(12),28,1975
Safety Information
[ Hazard Codes ]:
F: Flammable;Xi: Irritant;
[ Risk Phrases ]:
R11
[ Safety Phrases ]:
S26
[ RIDADR ]:
UN 1231 3/PG 2