2-[2-(1-Piperazinyl)ethoxy]ethanol

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Names

[ CAS No. ]:
13349-82-1

[ Name ]:
2-[2-(1-Piperazinyl)ethoxy]ethanol

[Synonym ]:
1-[2-(2-Hydroxyethoxy)ethyl]piperazine
HEP
Ethanol, 2-[2-(1-piperazinyl)ethoxy]-
1-Hydroxyethoxyethylpiperazine
N-HYDROXYETHOXYETHYL PIPERAZINE
Quetiapine intermediate
2-[2-(1-Piperazinyl)ethoxy]ethanol
MFCD00074931
T6M DNTJ D2O2Q
2-(2-(Piperazin-1-yl)ethoxy)ethanol
1-piperazidine
1-[2-(2-HYDROXYETHOXY)-ETHYL] PIPERAZINE
Quetiapine Impurity 44

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
305.7±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C8H18N2O2

[ Molecular Weight ]:
174.241

[ Flash Point ]:
132.2±23.2 °C

[ Exact Mass ]:
174.136826

[ PSA ]:
44.73000

[ LogP ]:
-1.15

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.474

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • dea
  • Diglycolamine
  • N-Carbethoxy Piperazine
  • 2-(2-Chloroethoxy)ethanol

DownStream

  • Isopropanol
  • Quetiapine
  • [4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]-(2-iodophenyl)methanone

Related Compounds

  • 2-(2-(4-(2-((2-CHLORO-10-PHENOTHIAZINYL) METHYL)PROPYL)-1-PIPERAZINYL)-ETHOXY)ETHANOL
  • 2-[2-[4-[2-[(p-Chloro-α-phenylbenzyl)amino]ethyl]-1-piperazinyl]ethoxy]ethanol
  • Hydroxyzine-d8 (hydrochloride)
  • Hydroxyzine dihydrochloride
  • 5-oxo-L-proline, compound with 2-[2-[4-(4-chlorobenzhydryl)-1-piperazinyl]ethoxy]ethanol (2:1)
  • FLUPENTIXOL IMPURITY D
  • {3-Oxo-2,8-dioxaspiro[4.6]undecan-1-yl}methanesulfonyl chloride
  • 2-[5-(4-ethylphenyl)-2-oxo-2H-1,3-dioxol-4-yl]acetic acid
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1,1-Difluoro-2-[3-(methoxymethyl)furan-2-yl]propan-2-amine
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methyl-3-({1-[(5-methyl-1,2,4-oxadiazol-3-yl)methyl]piperidin-4-yl}methoxy)pyrazine
  • 1-methyl-4-nitro-5-[(pyrrolidin-2-yl)methyl]-1H-pyrazole
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 4-[5-Fluoro-2-(trifluoromethyl)phenoxy]-4-methylpiperidine
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-