2-[2-(1-Piperazinyl)ethoxy]ethanol

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Names

[ CAS No. ]:
13349-82-1

[ Name ]:
2-[2-(1-Piperazinyl)ethoxy]ethanol

[Synonym ]:
1-[2-(2-Hydroxyethoxy)ethyl]piperazine
HEP
Ethanol, 2-[2-(1-piperazinyl)ethoxy]-
1-Hydroxyethoxyethylpiperazine
N-HYDROXYETHOXYETHYL PIPERAZINE
Quetiapine intermediate
2-[2-(1-Piperazinyl)ethoxy]ethanol
MFCD00074931
T6M DNTJ D2O2Q
2-(2-(Piperazin-1-yl)ethoxy)ethanol
1-piperazidine
1-[2-(2-HYDROXYETHOXY)-ETHYL] PIPERAZINE
Quetiapine Impurity 44

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
305.7±0.0 °C at 760 mmHg

[ Molecular Formula ]:
C8H18N2O2

[ Molecular Weight ]:
174.241

[ Flash Point ]:
132.2±23.2 °C

[ Exact Mass ]:
174.136826

[ PSA ]:
44.73000

[ LogP ]:
-1.15

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.474

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

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Precursor & DownStream

Precursor

  • dea
  • Diglycolamine
  • N-Carbethoxy Piperazine
  • 2-(2-Chloroethoxy)ethanol

DownStream

  • Isopropanol
  • Quetiapine
  • [4-[2-(2-hydroxyethoxy)ethyl]piperazin-1-yl]-(2-iodophenyl)methanone

Related Compounds

  • 2-(2-(4-(2-((2-CHLORO-10-PHENOTHIAZINYL) METHYL)PROPYL)-1-PIPERAZINYL)-ETHOXY)ETHANOL
  • 2-[2-[4-[2-[(p-Chloro-α-phenylbenzyl)amino]ethyl]-1-piperazinyl]ethoxy]ethanol
  • Hydroxyzine-d8 (hydrochloride)
  • Hydroxyzine dihydrochloride
  • 5-oxo-L-proline, compound with 2-[2-[4-(4-chlorobenzhydryl)-1-piperazinyl]ethoxy]ethanol (2:1)
  • FLUPENTIXOL IMPURITY D