Aqueous ammonia

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Names

[ CAS No. ]:
1336-21-6

[ Name ]:
Aqueous ammonia

[Synonym ]:
aq. ammonia
EINECS 215-647-6
MFCD00066650
Ammonia aqueous
ammonia water
aqueous ammonia
Ammonium hydroxide
NH4OH
ammonia hydroxide

Chemical & Physical Properties

[ Density]:
0.91 g/mL at 20 °C

[ Boiling Point ]:
36°C

[ Melting Point ]:
-77°C

[ Molecular Formula ]:
H5NO

[ Molecular Weight ]:
35.046

[ Exact Mass ]:
35.037113

[ PSA ]:
23.06000

[ LogP ]:
0.19940

[ Vapour Pressure ]:
5990mmHg at 25°C

[ Stability ]:
Stable. Incompatible with copper, copper alloys, acids, galvanised iron, zinc, aluminium, bronze, dimethyl sulphate, mercury, alkali metals.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BQ9625000
CHEMICAL NAME :
Ammonium hydroxide
CAS REGISTRY NUMBER :
1336-21-6
LAST UPDATED :
199710
DATA ITEMS CITED :
19
MOLECULAR FORMULA :
H5-N-O
MOLECULAR WEIGHT :
35.06
WISWESSER LINE NOTATION :
Z& Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Rinsed with water
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Human
DOSE/DURATION :
43 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LCLo - Lowest published lethal concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Human
DOSE/DURATION :
5000 ppm
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Human
DOSE/DURATION :
408 ppm
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Lungs, Thorax, or Respiration - acute pulmonary edema
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
350 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes Liver - other changes Kidney, Ureter, Bladder - other changes
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
91 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - coma Lungs, Thorax, or Respiration - respiratory stimulation
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
10 mg/disc
REFERENCE :
ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 76,475,1958 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 06145 No. of Facilities: 85664 (estimated) No. of Industries: 297 No. of Occupations: 161 No. of Employees: 735671 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 06145 No. of Facilities: 66188 (estimated) No. of Industries: 326 No. of Occupations: 188 No. of Employees: 1022551 (estimated) No. of Female Employees: 379643 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314-H335-H412

[ Precautionary Statements ]:
P260-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R34;R50

[ Safety Phrases ]:
S26-S36/37/39-S45-S61

[ RIDADR ]:
UN 2672 8/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
BQ9625000

[ Packaging Group ]:
III

[ Hazard Class ]:
8

[ HS Code ]:
2814200010

Synthetic Route

Precursor & DownStream

Precursor

  • sodium nitrate
  • Boron nitride
  • Water

DownStream

  • 3-Amino-6-fluoropyridazine
  • 1-ACETYL-5-INDOLINESULFONAMIDE
  • 6-Bromo-2-chloro-4-methylquinoline
  • 2'-Aminoacetophenone
  • Ethyl 5-methyl-1,2-oxazole-3-carboxylate
  • 2-Chloroquinazolin-4-amine
  • 2-bromo-2-fluoroacetamide
  • N-Methyl-N-vinylacetamide
  • (3-aminopropyl)imidazole
  • 5-Bromoisoquinoline

Customs

[ HS Code ]: 2814200010

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