9-(p-DIMETHYLAMINOANILINO)ACRIDINE
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Names
[ CAS No. ]:
13365-38-3
[ Name ]:
9-(p-DIMETHYLAMINOANILINO)ACRIDINE
[Synonym ]:
ACRIDINE,9-(p-DIMETHYLAMINOANILINO)
9-(p-Dimethylaminoanilino)acridine
WIN 1701
N'-9-Acridinyl-N,N-dimethyl-1,4-benzenediamine
9-((p-(Dimethylamino)phenyl)amino)acridine
9-[(4-Dimethylamino-phenyl)-amino]-acridin
Acridine,9-((p-(dimethylamino)phenyl)amino)
Chemical & Physical Properties
[ Density]:
1.229g/cm3
[ Boiling Point ]:
490.2ºC at 760 mmHg
[ Molecular Formula ]:
C21H19N3
[ Molecular Weight ]:
313.39600
[ Flash Point ]:
250.3ºC
[ Exact Mass ]:
313.15800
[ PSA ]:
28.16000
[ LogP ]:
5.27060
[ Vapour Pressure ]:
9.34E-10mmHg at 25°C
[ Index of Refraction ]:
1.748
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AR9100000
- CHEMICAL NAME :
- Acridine, 9-(p-dimethylaminoanilino)-
- CAS REGISTRY NUMBER :
- 13365-38-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C21-H19-N3
- MOLECULAR WEIGHT :
- 313.43
- WISWESSER LINE NOTATION :
- T C666 BNJ IMR DN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 15 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 80970 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Gastrointestinal - changes in structure or function of salivary glands
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - convulsions or effect on seizure threshold Cardiac - pulse rate
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 35 mg/kg/28D-I
- TOXIC EFFECTS :
- Cardiac - arrhythmias (including changes in conduction) Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Gastrointestinal - changes in structure or function of salivary glands
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 35 mg/kg/28D-I
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Gastrointestinal - changes in structure or function of salivary glands Blood - pigmented or nucleated red blood cells
MUTATION DATA
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lymphocyte
- DOSE/DURATION :
- 2 umol/L
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,170,1981
Safety Information
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%