1-Aminonaphthalene
Suppliers
Names
[ CAS No. ]:
134-32-7
[ Name ]:
1-Aminonaphthalene
[Synonym ]:
1-amino-naphthalene
1-Naftylamin
naphthalen-1-NH2
Aminogen I
α-Naphthylamine [UN2077] [Poison]
a-Naphthylamine
naphthalen-1-ylamine
Naphthaleneamine
naphthyl amine
naphthalen-1-amine
1-Naftylamine
Naphthalidine
1-Naphthylamin
1-Naphthalenamine
naphthalenamine
naphthylamine
1-aminonaphthalene
1-Naftilamina
Naphtylamines
naphthalidam
EINECS 205-138-7
1-Naphthylamine
4-12-00-03009 (Beilstein Handbook Reference)
MFCD00004016
Chemical & Physical Properties
[ Density]:
1.114
[ Boiling Point ]:
301.0±0.0 °C at 760 mmHg
[ Melting Point ]:
47-50 °C(lit.)
[ Molecular Formula ]:
C10H9N
[ Molecular Weight ]:
143.185
[ Flash Point ]:
152.1±14.6 °C
[ Exact Mass ]:
143.073502
[ PSA ]:
26.02000
[ LogP ]:
2.17
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.694
[ Water Solubility ]:
Insoluble. 0.1698 g/100 mL
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- QM1400000
- CHEMICAL NAME :
- 1-Naphthylamine
- CAS REGISTRY NUMBER :
- 134-32-7
- BEILSTEIN REFERENCE NO. :
- 0386133
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 58
- MOLECULAR FORMULA :
- C10-H9-N
- MOLECULAR WEIGHT :
- 143.20
- WISWESSER LINE NOTATION :
- L66J BZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 96 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - muscle weakness
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1300 mg/kg/13W-I
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - leukemia
- TYPE OF TEST :
- Morphological transformation
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- DNA damage
- TYPE OF TEST :
- DNA inhibition
- TYPE OF TEST :
- Sister chromatid exchange
- TYPE OF TEST :
- Sperm Morphology
MUTATION DATA
- TEST SYSTEM :
- Mammal - dog
- REFERENCE :
- EVHPAZ EHP, Environmental Health Perspectives. (U.S. Government Printing Office, Supt of Documents, Washington, DC 20402) No.1- 1972- Volume(issue)/page/year: 49,125,1983 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,87,1974 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 4,87,1974 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,260,1987 TOXICOLOGY REVIEW KHZHAZ Khimiya i Zhizn. Chemistry and Life. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1965- Volume(issue)/page/year: 12(2),85,1976 TOXICOLOGY REVIEW ADCSAJ Advances in Chemistry Series. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) No.1- 1950- Volume(issue)/page/year: 13,271,1970 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD:skin-HUMAN CARCINOGEN, NO ASSIGNED TWA DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,24,1973 OSHA PEL (Construc):see CFR 29,1926.1104 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA-cancer suspect agent CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1004,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-SWEDEN;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO alpha-NAPHTHYLAMINE-air:CA use 29 CFR 1910.1004 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84304 No. of Facilities: 66 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 610 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84304 No. of Facilities: 268 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 2132 (estimated) No. of Female Employees: 1796 (estimated)
Safety Information
[ Symbol ]:
GHS06, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H310-H350-H411
[ Precautionary Statements ]:
P201-P273-P280-P302 + P350-P310
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
C,N,Xn
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45-S61-S24
[ RIDADR ]:
UN 2790 8/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
QM1400000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
Synthetic Route
Precursor & DownStream
Precursor
DownStream
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