Erythromycin 2'-Propionate

Suppliers

Names

[ CAS No. ]:
134-36-1

[ Name ]:
Erythromycin 2'-Propionate

[Synonym ]:
EINECS 205-140-8
O''-Propionyl-erythromycin
erythromycin A 2'-propionate
Propionyl erythromicin
2'-Propionylerythromycin
Propionylerythromycin
ERYTHROMYCIN PROPIONATE
2'-propionoylerythromycin

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Boiling Point ]:
827.7ºC at 760mmHg

[ Melting Point ]:
122-126ºC

[ Molecular Formula ]:
C40H71NO14

[ Molecular Weight ]:
789.99000

[ Flash Point ]:
454.4ºC

[ Exact Mass ]:
789.48700

[ PSA ]:
199.98000

[ LogP ]:
2.74650

[ Vapour Pressure ]:
8.87E-32mmHg at 25°C

[ Index of Refraction ]:
1.527

[ Storage condition ]:
-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KF5190000
CHEMICAL NAME :
Erythromycin, 2'-propionate
CAS REGISTRY NUMBER :
134-36-1
LAST UPDATED :
199103
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C40-H71-N-O14
MOLECULAR WEIGHT :
790.12

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 6,354,1958/1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 6,354,1958/1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2870 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 6,354,1958/1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 6,354,1958/1959

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • Methyl (S)-2-amino-2-(3,4-difluorophenyl)acetate
  • Ethanone, 1-[3-amino-4-[(3-chloro-4-methylphenyl)amino]phenyl]-
  • Methyl 2-(4-(dimethylamino)phenyl)quinazoline-4-carboxylate
  • 2-(Pyrimidin-4-yl)quinazoline-4-carboxylic acid
  • Benzyl 3,3-dimethyl-5-[1-[(2-methylpropan-2-yl)oxycarbonyl]piperidin-4-yl]oxy-1,4-dihydroisoquinoline-2-carboxylate
  • Methyl1-(methylsulfonamido)cyclopentanecarboxylate
  • 1-(3-Chlorobenzyl)-5-phenylimidazolidin-2-one
  • Methyl (S)-2-amino-2-(2-chloro-6-fluorophenyl)acetate
  • rac-ethyl (1R,3S)-1-amino-3-methylcyclohexane-1-carboxylate
  • (1S,2S)-2-{[(pyridin-3-yl)methyl]amino}cyclohexan-1-ol
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