Erythromycin 2'-Propionate

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Names

[ CAS No. ]:
134-36-1

[ Name ]:
Erythromycin 2'-Propionate

[Synonym ]:
EINECS 205-140-8
O''-Propionyl-erythromycin
erythromycin A 2'-propionate
Propionyl erythromicin
2'-Propionylerythromycin
Propionylerythromycin
ERYTHROMYCIN PROPIONATE
2'-propionoylerythromycin

Chemical & Physical Properties

[ Density]:
1.19g/cm3

[ Boiling Point ]:
827.7ºC at 760mmHg

[ Melting Point ]:
122-126ºC

[ Molecular Formula ]:
C40H71NO14

[ Molecular Weight ]:
789.99000

[ Flash Point ]:
454.4ºC

[ Exact Mass ]:
789.48700

[ PSA ]:
199.98000

[ LogP ]:
2.74650

[ Vapour Pressure ]:
8.87E-32mmHg at 25°C

[ Index of Refraction ]:
1.527

[ Storage condition ]:
-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KF5190000
CHEMICAL NAME :
Erythromycin, 2'-propionate
CAS REGISTRY NUMBER :
134-36-1
LAST UPDATED :
199103
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C40-H71-N-O14
MOLECULAR WEIGHT :
790.12

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 6,354,1958/1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 6,354,1958/1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2870 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 6,354,1958/1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 6,354,1958/1959

Safety Information

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • (8-fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)[4-(1H-tetrazol-1-yl)phenyl]methanone
  • 7-[2-(8-fluoro-1,3,4,5-tetrahydro-2H-pyrido[4,3-b]indol-2-yl)-2-oxoethoxy]-4-methyl-2H-chromen-2-one
  • 2,4,6-Trimethyl-N-(2-methylpropyl)benzenamine
  • N-(3-fluorobenzyl)-1H-imidazole-1-carboxamide
  • 3,6-dichloro-N-{2-[(2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl)oxy]ethyl}pyridine-2-carboxamide
  • 2-(6-chloro-1H-indol-1-yl)-N-[2-(4-sulfamoylphenyl)ethyl]acetamide
  • (2E)-N-[(2E)-4-methyl-5-(3-phenyl-1,2,4-oxadiazol-5-yl)-1,3-thiazol-2(3H)-ylidene]-3-phenylprop-2-enamide
  • N-[2-(5-chloro-1H-indol-3-yl)ethyl]-2-[2-(1H-pyrrol-1-yl)-1,3-thiazol-4-yl]acetamide
  • 2-(3-methylbutyl)-1,3-dioxo-N-[4-(1H-1,2,4-triazol-1-ylmethyl)phenyl]-2,3-dihydro-1H-isoindole-5-carboxamide
  • 4-{[(5-methoxy-1H-indol-1-yl)acetyl]amino}benzamide
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