Diethylpropion Hydrochloride

Names

[ CAS No. ]:
134-80-5

[ Name ]:
Diethylpropion Hydrochloride

[Synonym ]:
1-Propanone, 2-(diethylamino)-1-phenyl-, hydrochloride (1:1)
Prefamone
Keramik
Keramin
Diethylpropione hydrochloride
2-(diéthylamino)-1-phénylpropan-1-one chlorhydrate
2-(Diethylamino)-1-phenyl-1-propanone hydrochloride (1:1)
2-(Diethylamino)-1-phenylpropan-1-onhydrochlorid
Diethylpropion Hydrochloride
Regenon
ANOREX
Danylen
Frekentine
Tylinal
2-(diethylamino)-1-phenylpropan-1-one,hydrochloride
EINECS 205-156-5
2-(diethylamino)-1-phenylpropan-1-one hydrochloride
2-Diethylaminopropiophenone Hydrochloride
a-Benzoyltriethylamine Hydrochloride
Anfamon
2-(Diethylamino)-1-phenylpropan-1-one hydrochloride (1:1)
UNII:19V2PL39NG
Amfepramone HCL
Magrene
Modulor
Parabolin

Chemical & Physical Properties

[ Density]:
0.972g/cm3

[ Boiling Point ]:
292ºC at 760mmHg

[ Melting Point ]:
180-181ºC

[ Molecular Formula ]:
C13H20ClNO

[ Molecular Weight ]:
241.757

[ Flash Point ]:
95.4ºC

[ Exact Mass ]:
241.123337

[ PSA ]:
20.31000

[ LogP ]:
3.40160

[ Vapour Pressure ]:
0.00189mmHg at 25°C

[ Storage condition ]:
Controlled Substance, -20°C Freezer

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UH0360000
CHEMICAL NAME :
Propiophenone, 2-(diethylamino)-, hydrochloride
CAS REGISTRY NUMBER :
134-80-5
LAST UPDATED :
199606
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C13-H19-N-O.Cl-H
MOLECULAR WEIGHT :
241.79
WISWESSER LINE NOTATION :
2N2&Y1&VR &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 17,373,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
139 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 17,121,1960
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
385 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 17,373,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 17,373,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
450 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - excitement Skin and Appendages - hair
REFERENCE :
APSXAS Acta Pharmaceutica Suecica. (Apotekarsocieteten-Farmacevtiska Foereningen, Box 1136, S-111, 81 Stockholm, Sweden) V.1- 1964- Volume(issue)/page/year: 4,37,1967
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59, 1945-86. For publisher information, see PHTOEH Volume(issue)/page/year: 17,182,1960

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302 + H312 + H332

[ Precautionary Statements ]:
P261-P280-P301 + P312 + P330

[ Hazard Codes ]:
F,T

[ Risk Phrases ]:
11-23/24/25-39/23/24/25-20/21/22

[ Safety Phrases ]:
7-16-36/37-45-36

[ RIDADR ]:
UN1230 - class 3 - PG 2 - Methanol, solution

[ HS Code ]:
2922399090

Precursor & DownStream

Precursor

DownStream

  • Diethylamine
  • 1-Phenylpropane-1,2-dione
  • benzoic acid

Customs

[ HS Code ]: 2922399090

[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%


Related Compounds

  • rac Diethylpropion-d10 Hydrochloride
  • Tyrocidine, hydrochloride
  • Triprolidine hydrochloride
  • Minoxidil hydrochloride
  • neomycin hydrochloride
  • dodecylamine hydrochloride