ponasterone A

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Names

[ CAS No. ]:
13408-56-5

[ Name ]:
ponasterone A

[Synonym ]:
25-Deoxyecdysterone
(2b,3b,5b,22R)-2,3,14,20,22-Pentahydroxycholest-7-en-6-one
ponasterone A
(2β,3β,5β,22R)-2,3,14,20,22-Pentahydroxycholest-7-en-6-one
Cholest-7-en-6-one, 2,3,14,20,22-pentahydroxy-, (2β,3β,5β,22R)-
25-Deoxy-20-hydroxyecdysone
MFCD00272144
(2S,3R,5R,9R,10R,13R,14S,17S)-17-[(2R,3R)-2,3-dihydroxy-6-methylheptan-2-yl]-2,3,14-trihydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-6-one

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
640.5±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C27H44O6

[ Molecular Weight ]:
464.635

[ Flash Point ]:
355.2±28.0 °C

[ Exact Mass ]:
464.313782

[ PSA ]:
118.22000

[ LogP ]:
1.55

[ Vapour Pressure ]:
0.0±4.3 mmHg at 25°C

[ Index of Refraction ]:
1.582

[ Storage condition ]:
−20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

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Retrovirology 12 , 4, (2015)

Macrophages are key targets of HIV-1 infection. We have previously described that the expression of CC chemokine ligand 2 (CCL2) increases during monocyte differentiation to macrophages and it is furt...

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Retrovirology 12 , 50, (2015)

Maraviroc (MVC) is an allosteric CCR5 inhibitor used against HIV-1 infection. While MVC-resistant viruses have been identified in patients, it still remains incompletely known how they adjust their CD...

Genome-wide promoter binding profiling of protein phosphatase-1 and its major nuclear targeting subunits.

Nucleic Acids Res. 43 , 5771-84, (2015)

Protein phosphatase-1 (PP1) is a key regulator of transcription and is targeted to promoter regions via associated proteins. However, the chromatin binding sites of PP1 have never been studied in a sy...


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Related Compounds

  • ponasterone A diacetonide
  • Camellianin A
  • lactococcin A
  • maquiroside A
  • actinoplanone A
  • Influenza A virus-IN-4
  • 5-(bromomethyl)-N-(3-chlorophenyl)-4-methyl-4,5-dihydro-1,3-thiazol-2-amine
  • 2-{[(3-Bromo-2-cyclopropylpropyl)sulfanyl]methyl}-3-methylfuran
  • (5-Bromo-4,4-dimethylpentan-2-yl)benzene
  • (3-Bromo-1,1-difluoro-2-methylpropyl)benzene
  • 4-(3-bromoprop-1-en-2-yl)-3-phenyl-1H-pyrazole
  • [3-(Bromomethyl)-2-methylbuta-1,3-dien-1-yl]benzene
  • tert-butyl N-[5-(3-bromoprop-1-en-2-yl)pyrimidin-2-yl]carbamate
  • tert-butyl N-[4-(3-bromo-2,2-dimethylpropyl)cyclohexyl]carbamate
  • tert-butyl N-[3-(1-bromopropan-2-yl)-4-methoxyphenyl]carbamate
  • tert-butyl N-[2-(chloromethyl)prop-2-en-1-yl]-N-(propan-2-yl)carbamate
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