Nifurpirinol

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Names

[ CAS No. ]:
13411-16-0

[ Name ]:
Nifurpirinol

[Synonym ]:
Furanace
Furpirinol
Furpirinol Furpyrinol {6-[2-(5-Nitro-2-furanyl)vinyl]-2-pyridinyl}methanol
Furpyrinol
Nifurpirinol
Furanace-10

Chemical & Physical Properties

[ Density]:
1.412 g/cm3

[ Boiling Point ]:
416.3ºC at 760 mmHg

[ Melting Point ]:
170-171°

[ Molecular Formula ]:
C12H10N2O4

[ Molecular Weight ]:
246.21900

[ Flash Point ]:
205.6ºC

[ Exact Mass ]:
246.06400

[ PSA ]:
92.08000

[ LogP ]:
2.76870

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.695

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT5023000
CHEMICAL NAME :
2-Pyridinemethanol, 6-(2-(5-nitro-2-furyl)vinyl)-
CAS REGISTRY NUMBER :
13411-16-0
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C12-H10-N2-O4
MOLECULAR WEIGHT :
246.24
WISWESSER LINE NOTATION :
T6NJ B1Q F1U1- BT5OJ ENW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>2 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Human Lymphocyte
DOSE/DURATION :
10 umol/L
REFERENCE :
IDZAAW Japanese Journal of Genetics. Idengaku Zasshi. (Genetics Soc. of Japan, 111 Tanida, Mishima, Shizuoka-ken, Japan) V.1- 1921- Volume(issue)/page/year: 48,291,1973

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319

[ Precautionary Statements ]:
P305 + P351 + P338

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36

[ Safety Phrases ]:
26

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
UT5023000

[ HS Code ]:
2934999090

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Correlation of epizootiological observations with experimental data: chemical induction of chromatophoromas in the croaker, Nibea mitsukurii.

Natl. Cancer Inst. Monogr. 65 , 139-54, (1984)

Chromatophoromas in the croaker nibe, Nibea mitsukurii, are common neoplasms in feral fish which inhabit the shallow water in a unique geographic distribution along the Pacific coast of Japan. We unde...

[Disease of the fins of Rhamdia sapo. Isolation of the etiological agents and experimental infection].

Rev. Argent. Microbiol. 20(1) , 37-48, (1988)

During intensive culture of South-American catfish, Rhamdia sapo fingerlings an epizootic similar to fin rot was developed. Aeromonas hydrophila and Pseudomonas aeruginosa were isolated and they were ...

Mutagenicity of nifurpirinol (P-7138) in Escherichia coli WP2 and Salmonella typhimurium TA100.

Mutat. Res. 104(1-3) , 61-6, (1982)

Nifurpirinol, 6-hydroxymethyl-2-[2-(5-nitro-2-furyl)vinyl]pyridine, which has been widely used as an antibacterial drug against diseases of fish, was found to be a potent mutagen. The mutagenic effect...


More Articles

Related Compounds

  • Nifurpirinol
  • 4-Methyl-2-{4-[(pyrazin-2-yloxy)methyl]piperidin-1-yl}pyrimidine
  • 4-{3-[(4-bromo-1H-pyrazol-1-yl)methyl]azetidin-1-yl}-6-ethyl-5-fluoropyrimidine
  • 2-{4-[(Pyrazin-2-yloxy)methyl]piperidin-1-yl}pyrimidine
  • 5-Fluoro-2-{4-[(pyrazin-2-yloxy)methyl]piperidin-1-yl}pyrimidine
  • 3-(propan-2-yl)-N-[1-(pyridin-2-yl)azetidin-3-yl]-1,2,4-thiadiazol-5-amine
  • 4-{3-[(4-bromo-1H-pyrazol-1-yl)methyl]azetidin-1-yl}-2-(methylsulfanyl)pyrimidine
  • 4-(2-{4-[2-(Propan-2-yl)pyrimidin-4-yl]piperazin-1-yl}pyrimidin-4-yl)morpholine
  • 4-(4-{4-[2-(Propan-2-yl)pyrimidin-4-yl]piperazin-1-yl}pyrimidin-2-yl)morpholine
  • 4-(6-{4-[2-(Propan-2-yl)pyrimidin-4-yl]piperazin-1-yl}pyridazin-3-yl)morpholine
  • 3-(2-methoxyethyl)-5-[3-(2H-1,2,3-triazol-2-yl)azetidin-1-yl]-1,2,4-thiadiazole
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