5'-O-TBDMS-5-iodo-2'-deoxyuridine

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Names

[ CAS No. ]:
134218-81-8

[ Name ]:
5'-O-TBDMS-5-iodo-2'-deoxyuridine

[Synonym ]:
5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYURIDINE
5-iodo-5'-O-t-butyldimethylsilyl-2'-deoxyuridine
5'-O-(tert-butyldimethylsilyl)-2'-deoxy-5-iodouridine
5'-O-TBDMS-5-iodo-2'-deoxyuridine

Chemical & Physical Properties

[ Molecular Formula ]:
C15H25IN2O5Si

[ Molecular Weight ]:
468.35900

[ Exact Mass ]:
468.05800

[ PSA ]:
93.81000

[ LogP ]:
2.22370

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • idoxuridine
  • tert-Butyldimethylsilyl chloride
  • tert-Butyldimethylsilyl Trifluoromethanesulfonate

DownStream

  • 1-[(2R,4S,5R)-5-(hydroxymethyl)-4-phenylselanyloxolan-2-yl]-5-iodopyrimidine-2,4-dione
  • 1-[(2R,5S)-5-(hydroxymethyl)-2,5-dihydrofuran-2-yl]-5-iodopyrimidine-2,4-dione

Related Compounds

  • 5'-O-TBDMS-5-iodo-2'-deoxycytidine
  • 3'-O,5'-O,N3-tritoluoyl-5-iodo-2'-deoxyuridine
  • ((2R,3S,5R)-3-Acetoxy-5-(5-iodo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate
  • 5'-O-TBDMS-dU
  • 5'-O-(tert-Butyldimethylsilyl)-5-fluoro-2'-deoxyuridine
  • 5'-O-(DIMETHOXYTRITYL)-N4-DIMETHYLAMINOMETHYLIDENE-5-IODO-2'-DEOXYCYTIDINE