4-Hydroxy-6,7-dimethoxyquinoline

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Names

[ CAS No. ]:
13425-93-9

[ Name ]:
4-Hydroxy-6,7-dimethoxyquinoline

[Synonym ]:
MFCD07368026
4-Hydroxy-6,7-dimethoxyqunioline
4-Hydroxy-6,7-dimethoxyquinoline
6,7-DIMETHOXYQUINOLINE-4-OL

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
355.3±42.0 °C at 760 mmHg

[ Melting Point ]:
229 °C

[ Molecular Formula ]:
C11H11NO3

[ Molecular Weight ]:
205.210

[ Flash Point ]:
168.7±27.9 °C

[ Exact Mass ]:
205.073898

[ PSA ]:
51.58000

[ LogP ]:
2.61

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.558

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Amino-4,5-dimethoxyacetophenone
  • Ethyl formate
  • Triethyl orthoformate
  • Diphenyl oxide
  • 4-hydroxy-6,7-dimethoxyquinoline-3-carboxylic acid
  • 3,4-Dimethoxyaniline

DownStream

  • 4-Chloro-6,7-dimethoxyquinoline
  • 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
  • Cabozantinib (XL184, BMS-907351)
  • Cabozantinib malate (XL184)
  • Trifluoromethanesulfonic acid 6,7-dimethoxyquinolin-4-yl ester
  • 5-[(6,7-Dimethoxy-4-quinolinyl)oxy]-2-pyridinamine

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 3-carbethoxy-4-hydroxy-6,7-dimethoxyquinoline
  • 4-hydroxy-6,7-dimethoxyquinoline-3-carboxylic acid
  • ethyl 4-hydroxy-6,7-dimethoxyquinoline-3-carboxylate
  • 4-hydroxy-6,7-dioxo-1-benzofuran-5-carboxamide
  • 4-hydroxy-6,7-dimethylquinoline-2-carboxylic acid
  • 4-Hydroxy-6,7-dimethylcoumarin
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 2-{4-[(6-Methoxypyridin-3-yl)methyl]piperazin-1-yl}-4-(trifluoromethyl)pyrimidine
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 2-Hydroxy-3-methyl-3-(1-methylcyclohexyl)butanoic acid
  • 2-Methoxy-2-[1-(3-methyl-1,2-oxazol-5-yl)cyclopropyl]acetic acid
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 2-(aminomethyl)-N-(1-cyclobutylethyl)-2,3-dihydro-1-benzofuran-5-amine