Atorvastatin tert-Butyl Ester

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Names

[ CAS No. ]:
134395-00-9

[ Name ]:
Atorvastatin tert-Butyl Ester

[Synonym ]:
tert-butyl (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxyheptanoate
(|AR,|AR)-2-(4-Fluorophenyl)-|A,|A-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid 1,1-Dimethylethyl Ester
Atorvastatin tert-Butyl Ester
(3R,5R)-tert-Butyl 7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, 1,1-dimethylethyl ester, (βR,δR)-
2-Methyl-2-propanyl (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoate
Atorvastatin Impurity 3

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
721.0±60.0 °C at 760 mmHg

[ Melting Point ]:
66-68ºC

[ Molecular Formula ]:
C37H43FN2O5

[ Molecular Weight ]:
614.746

[ Flash Point ]:
389.9±32.9 °C

[ Exact Mass ]:
614.315613

[ PSA ]:
100.79000

[ LogP ]:
5.95

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.574

[ Storage condition ]:
-20C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Atorvastatin Acetonide tert-Butyl Ester
  • (4R,6R)-tert-Butyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate
  • tert-butyl 2-((7R,9R)-9-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-6,10-dioxaspiro[4.5]decan-7-yl)acetate
  • tert-butyl 2-((2R,4R)-4-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-1,5-dioxaspiro[5.5]undecan-2-yl)acetate
  • 4-Fluorobenzaldehyde
  • tert-butyl 2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate
  • cis-t-butyl-7-nitro-3,5-dihydroxy-heptanoate
  • tert-butyl 2-((2R,4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)ethyl)-2-phenyl-1,3-dioxan-4-yl)acetate
  • Benzenebutanamide,4-fluoro-α-(2-methyl-1-oxopropyl)-γ-oxo-N,β-diphenyl
  • 4-Methyl-3-oxo-N-phenylpentanamide

DownStream

  • Atorvastatin lactone
  • Atorvastatin
  • Atorvastatin Sodium

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 10-trans-Atorvastatin tert-Butyl Ester
  • Atorvastatin Acetonide tert-Butyl Ester
  • Norleucine tert-butyl ester hydrochloride
  • Moexipril tert-Butyl Ester Maleic Acid Salt
  • threonine tert-butyl ester
  • Defluoro Atorvastatin Acetonide tert-Butyl Ester