CA 074 TFA

Names

[ Name ]:
CA 074 TFA

[Synonym ]:
(L-3-trans-(Propylcarbamyl)oxirane-2-carbonyl)-L-isoleucyl-L-proline
L-TRANS-EPOXYSUCCINYL-ILE-PRO-OH PROPYLAMIDE
CATHEPSIN B INHIBITOR III
INHIBITOR FOR CATHEPSIN B

Chemical & Physical Properties

[ Density]:
1.267g/cm3

[ Boiling Point ]:
728.9ºC at 760mmHg

[ Molecular Formula ]:
C₁₈H₂₉N₃O₆

[ Molecular Weight ]:
383.43900

[ Flash Point ]:
394.7ºC

[ Exact Mass ]:
383.20600

[ PSA ]:
128.34000

[ LogP ]:
0.60620

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.539

[ Storage condition ]:
2-8℃

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Human cystatin C: a new biomarker of idiopathic pulmonary fibrosis?

Proteomics. Clin. Appl. 8(5-6) , 447-53, (2014)

Human idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disorder with a poor prognosis. The identification of a new and specific biomarker in bronchoalveolar lavage fluids (BALFs)...

Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety.

PLoS ONE 6(11) , e27197, (2011)

Redox cycling compounds have been reported to cause false positive inhibition of proteases in drug discovery studies. This kind of false positives can lead to unusually high hit rates in high-throughp...

Structural basis for development of cathepsin B-specific noncovalent-type inhibitor: crystal structure of cathepsin B-E64c complex.

Biochim. Biophys. Acta 1597(2) , 244-51, (2002)

In order to elucidate the substrate specificity of the Sn subsites (n=1-3) of cathepsin B, its crystal structure inhibited by E64c [(+)-(2S,3S)-3-(1-[N-(3-methylbutyl)amino]-leucylcarbonyl)oxirane-2-c...

CA 074 TFA

Suppliers

Names

Chemical & Physical Properties

MSDS

Click to get detail MSDS

Safety Information

Articles

Related Compounds