BW-B 70C

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Names

[ CAS No. ]:
134470-38-5

[ Name ]:
BW-B 70C

[Synonym ]:
70C
1-[(E)-4-[3-(4-fluorophenoxy)phenyl]but-3-en-2-yl]-1-hydroxyurea
N-[3-[3-4(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea

Chemical & Physical Properties

[ Density]:
1.295g/cm3

[ Boiling Point ]:
498.9ºC at 760 mmHg

[ Molecular Formula ]:
C17H17FN2O3

[ Molecular Weight ]:
316.32700

[ Flash Point ]:
255.5ºC

[ Exact Mass ]:
316.12200

[ PSA ]:
75.79000

[ LogP ]:
4.48990

[ Vapour Pressure ]:
8.96E-11mmHg at 25°C

[ Index of Refraction ]:
1.627

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YT3976666
CHEMICAL NAME :
Urea, N-(3-(3-(4-fluorophenoxy)phenyl)-1-methyl-2-propenyl) -N-hydroxy-
CAS REGISTRY NUMBER :
134470-38-5
LAST UPDATED :
199803
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C17-H17-F-N2-O3
MOLECULAR WEIGHT :
316.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
700 mg/kg/14D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - interstitial nephritis
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year: 69,480,1995
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
700 mg/kg/7D-I
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes primarily in glomeruli Kidney, Ureter, Bladder - proteinuria Blood - other changes
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 146,299,1997

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ RTECS ]:
YT3976666

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